The use of fibrin sealant in cerebrospinal fluid leakage

S. Pomeranz, S. Constantini, F. Umansky

Research output: Contribution to journalArticlepeer-review


Cerebrospinal fluid leakage is one of the central problems facing neurosurgeons, both due to its occasional difficulty in management and to the catastrophical significance of ensuing infection. An important tool emerging in the surgical management of CSF leakage is fibrin sealant, the natural coagulation product. Thirteen cases of CSF leakage, due to meningomyelocele, posttraumatic, and secondary to tumor, that were managed surgically with fibrin sealant are presented. Several of the cases were successfully operated upon following failure of conventional surgical techniques. Additional uses of fibrin sealant in neurosurgery are discussed.

Original languageEnglish
Pages (from-to)166-169
Number of pages4
Issue number6
StatePublished - 1991
Externally publishedYes


  • brain tumor
  • cerebrospinal fluid leakage
  • fibrin sealant
  • head trauma
  • meningomyelocele


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