The universal dinucleotide asymmetry rules in DNA and the amino acid codon choice

Ruth Nussinov*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

Natural DNA sequences were recently found to contain distinct nearest neighbor patterns. Hetero-dinucleotides were demonstrated to appear consistently more (less) than their mirror-image counterparts. This paper shows that this assymmetric behavior does not stem from the coding requirements of the DNA. It also shows some codon patterns in prokaryotic and eukaryotic genomes which came up in the course of this work.

Original languageEnglish
Pages (from-to)237-244
Number of pages8
JournalJournal of Molecular Evolution
Volume17
Issue number4
DOIs
StatePublished - Jul 1981
Externally publishedYes

Keywords

  • Dinucleotides
  • Genetic code
  • Prokaryotic, Eukaryotic, DNA

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