The treatment of patients with polycystic ovarian syndrome by in-vitro fertilization and embryo transfer: A comparison of results with those of patients with tubal infertility

J. Dor*, A. Shulman, D. Levran, Z. Ben-rafael, E. Rudak, S. Mashiach

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Sixteen patients with polycystic ovarian syndrome (PCO) were treated by in-vitro fertilization (26 treatment cycles). The results were compared with 37 normo-ovulatory women with tubal disease (37 treatment cycles). The oestradiol and progesterone levels were higher during the follicular phase in the PCO patients, but were statistically significantly higher only on the day after human chorionic gonadotrophin administration. Although more oocytes were recovered per cycle from the PC0 group (19.3 ± 6.1) than from the control group (5.4 ± 2.9) with P < 0.004, the mean numbers of embryos per cycle were similar in both groups (3.7 ± 2.4 versus 3.6 ± 2.2, respectively). The pregnancy rate was also comparable in both groups (30.7 versus 29.7%, respectively). The fact that more oocytes are recovered from PCO patients, balances their lower fertilization and cleavage rates. We conclude, therefore, that IVF treatment may be a viable solution for PCO patients resistant to an in-vivo protocol treatment regimes.

Original languageEnglish
Pages (from-to)816-818
Number of pages3
JournalHuman Reproduction
Volume5
Issue number7
DOIs
StatePublished - Oct 1990
Externally publishedYes

Keywords

  • IVF-embryo transfer
  • PCO
  • Tubal infertility

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