The thalidomide story: A new chapter

Research output: Contribution to journalReview articlepeer-review

Abstract

Thalidomide, a medication the use of which was banned about forty years ago due to its teratogenic effect, has returned into use due to its anti-angiogenic and immunomodulatory virtues. It is used now as a novel treatment in several malignant diseases as well as in the treatment of various inflammatory conditions. Recently it has been found that thalidomide may antagonize corneal blood vessels growth which is a late result of exposure to mustard gas. The story of thalidomide, which is very unusual, may serve as the snake symbol in medicine, to remind us about the possible double face of every medication, of which every physician should be aware.

Original languageEnglish
Pages (from-to)186-187+238
JournalHarefuah
Volume142
Issue number3
StatePublished - 1 Mar 2003

Keywords

  • AIDS
  • Angiogenesis
  • Angiogenesis therapy
  • Cancer
  • Thalidomide

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