The surface ultrastructure of Gaucher cells

M. Djaldetti, P. Fishman, H. Bessler

Research output: Contribution to journalArticlepeer-review


The Gaucher cells of seven patients with Gaucher's disease were examined by both transmission and scanning electron microscopy. The ultrastructure of the cells, as seen by transmission electron microscopy, did not differ from that reported in the literature. The surface structure varied not only in the different patients but also in the same individual. The cells were oval or round, most of them with a rough surface due to the presence of microvilli, ruffles, ridges, and blebs of various numbers and shapes. In two patients the Gaucher cells showed phagocytosis. The appearance of the surface ultrastructure of the Gaucher cells supports the accepted view that they are related to the cells of the reticuloendothelial system.

Original languageEnglish
Pages (from-to)146-150
Number of pages5
JournalAmerican Journal of Clinical Pathology
Issue number2
StatePublished - 1979
Externally publishedYes


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