The structure determination of two new acylphloroglucinols from Myrtus communis L.

Y. Kashman*, A. Rotstein, A. Lifshitz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Structures for two new acylpholorglucinols, myrtucommulone A (1) and myrtucommulone B (2) have been deduced from a detailed study of the NMR, IR and mass spectra of these substances, and their simple derivatives and degradation products. The compounds contain phloroglucinol and syncarpic acid (1,1,3,3, tetramethyl-cyclohexa-2,4,6-trione) residues, and are closely related chemically to fern constituents such as filixic acid, as well as to kosins and uliginosins isolated from higher plants. Compounds 1 and 2 are unique in having an isobutyl bridge connecting the rings. Compound 1 exhibits strong antibacterial activity against gram positive bacteria.

Original languageEnglish
Pages (from-to)991-997
Number of pages7
JournalTetrahedron
Volume30
Issue number8
DOIs
StatePublished - 1974
Externally publishedYes

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