The selective effect of tunicamycin on the secretion of IgM and IgG produced by the same cells

Cila Blatt, Joseph Haimovich*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Cells of the hybridoma cell line X 63/38 C‐13 secreting both IgM and IgG have been used in studies on the importance of the carbohydrate moieties of the Ig molecules for their secretion. It has been found that the secretion of the IgM produced in the presence of the glycosylation inhibitor tunicamycin was strongly inhibited, while the secretion of the IgG produced by the same cells was only slightly affected.

Original languageEnglish
Pages (from-to)65-66
Number of pages2
JournalEuropean Journal of Immunology
Volume11
Issue number1
DOIs
StatePublished - Jan 1981

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