The saliva of the medicinal leech hirudo medicinalis-II. inhibition of platelet aggregation and of leukocyte activity and examination of reputed anaesthetic effects

Meir Rigbi, Haim Levy, Amiram Eldor, Fuad Iraqi, Mira Teitelbaum, Miriam Orevi, Amnon Horovitz, Rachel Galun

Research output: Contribution to journalArticlepeer-review

Abstract

1. Leech saliva inhibits platelet aggregation induced by collagen, ADP and epinephrine. 2. Leech saliva inhibits Superoxide production by neutrophils stimulated by tetradecanoyl phorbol acetate or polyhistidine. The effect is due in part at least to eglin. 3. Reputed anaesthetic effects of leech saliva were not detected.

Original languageEnglish
Pages (from-to)95-98
Number of pages4
JournalComparative biochemistry and physiology. C: Comparative pharmacology
Volume88
Issue number1
DOIs
StatePublished - 1987
Externally publishedYes

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