The role of speckle strain echocardiography in the diagnosis of early subclinical cardiac injury in cancer patients—is there more than just left ventricle global longitudinal strain?

Michal Laufer-Perl, Dan Gilon, Livia Kapusta, Zaza Iakobishvili

Research output: Contribution to journalReview articlepeer-review

Abstract

With the improvement in survival rate, cardiotoxicity has emerged as a significant adverse effect of cancer therapy. Early diagnosis of subclinical cardiac injury may allow the initiation of cardioprotective therapy and preventing the interruption of optimal cancer therapy and the development of irreversible cardiac dysfunction. In this article, we review the role of two-dimensional speckle tracking echocardiography (2D-STE), beyond the common left ventricle global longitudinal strain in the diagnosis of early subclinical cardiac injury in patients treated with cancer therapies.

Original languageEnglish
Article number154
Pages (from-to)1-10
Number of pages10
JournalJournal of Clinical Medicine
Volume10
Issue number1
DOIs
StatePublished - 1 Jan 2021

Keywords

  • Cardio-oncology
  • Cardiotoxicity
  • Diastolic strain
  • Global longitudinal strain
  • Left atrial strain
  • Right ventricle strain
  • Speckle tracking

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