The role of routine pelvic lymph node sampling in patients with stage I endometrial carcinoma: Second thoughts

Amiram Bar-Am, Ilan Gil Ron, Michael Kuperminc, Ilan Gal, Ariel Jaffa, Felix Kovner, Neli Wigler, Moshe Inbar, Joseph Lessing

Research output: Contribution to journalArticlepeer-review

Abstract

Background and methods. The cases of 245 patients diagnosed during 1980-1989 with stage I endometrial carcinoma were retrospectively reviewed in order to assess the contribution of lymph node sampling (LNS) to both course of treatment and outcome. The 183 women treated by gyneco-oncologic surgeons had undergone the standard surgical procedure of total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO) and pelvic lymph node sampling (LNS). Sixty-two other women, treated by gynecologists, received only TAH and BSO. Of women who had received TAH + BSO + LNS, 105 (57.4%) were referred for adjuvant radiotherapy on the basis of one or any combination of high grade histology (G2 or G3), myometrial invasion to a depth of 50% or more and LNS positivity. Of the group who had not had LNS, 37 (59.7%) likewise received adjuvant radiotherapy but on the bases of histology and/or depth of invasion. Results and conclusions. Recurrence and survival over a mean follow-up period of 7.5 years (range 5-15 years) showed no significant differences between the patients who underwent LNS and those who did not. Of 43 recurrences, six were among 'low risk' women (those with both minimal invasion and low grade histology), suggesting a special need among this group for the additional staging information which LNS may provide.

Original languageEnglish
Pages (from-to)347-350
Number of pages4
JournalActa Obstetricia et Gynecologica Scandinavica
Volume77
Issue number3
DOIs
StatePublished - 1998

Keywords

  • Histological grade
  • Lymph node sampling (LNS)
  • Myometrial invasion
  • Stage I endometrial carcinoma

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