The role of Mitogen activated protein kinase (MAPK) in sperm functions

Tal Almog, Zvi Naor*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


The generation of mature spermatozoa in the epididymis includes the activation of the MAPK cascade in a complex manner. MAPKs are thought to be involved in the regulation of transcription and ectoplasmic specialization (ES) in the testis. MAPKs also regulate mature spermatozoa flagellar motility, hyperactivation and the acrosome reaction. Here we review the current data regarding the functions of MAPKs in spermatogenesis and in mature spermatozoa.

Original languageEnglish
Pages (from-to)239-243
Number of pages5
JournalMolecular and Cellular Endocrinology
Issue number2
StatePublished - 27 Jan 2010


  • ERK
  • MAPK
  • Sperm motility
  • Spermatogenesis
  • Spermatozoa
  • p38


Dive into the research topics of 'The role of Mitogen activated protein kinase (MAPK) in sperm functions'. Together they form a unique fingerprint.

Cite this