The role of Mitogen activated protein kinase (MAPK) in sperm functions

Tal Almog; Zvi Naor

doi:10.1016/j.mce.2009.05.009

The role of Mitogen activated protein kinase (MAPK) in sperm functions

Tal Almog, Zvi Naor^*

^*Corresponding author for this work

Biochemistry Molecular Biology

Tel Aviv University

Research output: Contribution to journal › Review article › peer-review

68 Scopus citations

Abstract

The generation of mature spermatozoa in the epididymis includes the activation of the MAPK cascade in a complex manner. MAPKs are thought to be involved in the regulation of transcription and ectoplasmic specialization (ES) in the testis. MAPKs also regulate mature spermatozoa flagellar motility, hyperactivation and the acrosome reaction. Here we review the current data regarding the functions of MAPKs in spermatogenesis and in mature spermatozoa.

Original language	English
Pages (from-to)	239-243
Number of pages	5
Journal	Molecular and Cellular Endocrinology
Volume	314
Issue number	2
DOIs	https://doi.org/10.1016/j.mce.2009.05.009
State	Published - 27 Jan 2010

Keywords

ERK
MAPK
Sperm motility
Spermatogenesis
Spermatozoa
p38

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10.1016/j.mce.2009.05.009

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The role of Mitogen activated protein kinase (MAPK) in sperm functions

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Keywords

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