Abstract
The generation of mature spermatozoa in the epididymis includes the activation of the MAPK cascade in a complex manner. MAPKs are thought to be involved in the regulation of transcription and ectoplasmic specialization (ES) in the testis. MAPKs also regulate mature spermatozoa flagellar motility, hyperactivation and the acrosome reaction. Here we review the current data regarding the functions of MAPKs in spermatogenesis and in mature spermatozoa.
Original language | English |
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Pages (from-to) | 239-243 |
Number of pages | 5 |
Journal | Molecular and Cellular Endocrinology |
Volume | 314 |
Issue number | 2 |
DOIs | |
State | Published - 27 Jan 2010 |
Keywords
- ERK
- MAPK
- Sperm motility
- Spermatogenesis
- Spermatozoa
- p38