The role of insulin pump therapy for type 2 diabetes mellitus

Zohar Landau, Itamar Raz*, Julio Wainstein, Yosefa Bar-Dayan, Avivit Cahn

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Many patients with type 2 diabetes fail to achieve adequate glucose control despite escalation of treatment and combinations of multiple therapies including insulin. Patients with long-standing type 2 diabetes often suffer from the combination of severe insulin deficiency in addition to insulin resistance, thereby requiring high doses of insulin delivered in multiple injections to attain adequate glycemic control. Insulin-pump therapy was first introduced in the 1970s as an approach to mimic physiological insulin delivery and attain normal glucose in patients with type 1 diabetes. The recent years have seen an increase in the use of this technology for patients with type 2 diabetes. This article summarizes the clinical studies evaluating insulin pump use in patients with type 2 diabetes and discusses the benefits and shortcomings of pump therapy in this population.

Original languageEnglish
Article numbere2822
JournalDiabetes/Metabolism Research and Reviews
Volume33
Issue number1
DOIs
StatePublished - 1 Jan 2017

Keywords

  • continuous subcutaneous insulin infusion
  • diabetes control
  • insulin pump
  • multiple daily injections
  • type 2 diabetes

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