The role of human basolateral amygdala in ambiguous social threat perception

Beatrice De Gelder; David Terburg; Barak Morgan; Ruud Hortensius; Dan J. Stein; Jack van Honk

doi:10.1016/j.cortex.2013.12.010

The role of human basolateral amygdala in ambiguous social threat perception

Beatrice De Gelder^*, David Terburg, Barak Morgan, Ruud Hortensius, Dan J. Stein, Jack van Honk

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Previous studies have shown that the amygdala (AMG) plays a role in how affective signals are processed. Animal research has allowed this role to be better understood and has assigned to the basolateral amygdala (BLA) an important role in threat perception. Here we show that, when passively exposed to bodily threat signals during a facial expressions recognition task, humans with bilateral BLA damage but with a functional central-medial amygdala (CMA) have a profound deficit in ignoring task-irrelevant bodily threat signals.

Original language	English
Pages (from-to)	28-34
Number of pages	7
Journal	Cortex
Volume	52
Issue number	1
DOIs	https://doi.org/10.1016/j.cortex.2013.12.010
State	Published - Mar 2014
Externally published	Yes

Funding

Funders	Funder number
Medical Research Council
Department of Science and Technology, Ministry of Science and Technology, India
H2020 Future and Emerging Technologies
Seventh Framework Programme	295673
University of Cape Town
John D. and Catherine T. MacArthur Foundation
European Research Council
European Commission	249858
Hope for Depression Research Foundation	RGA # 9-015
Netherlands Society of Scientific Research	056 24-010

Keywords

Amygdala
Basolateral amygdala
Body emotion expressions
Emotion
Urbach-Wiethe disease

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10.1016/j.cortex.2013.12.010

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AU - Stein, Dan J.

AU - van Honk, Jack

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KW - Urbach-Wiethe disease

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The role of human basolateral amygdala in ambiguous social threat perception

Abstract

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Keywords

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