TY - JOUR
T1 - The role of bile acid excretion in atherosclerotic coronary artery disease
AU - Charach, Gideon
AU - Rabinovich, Alexander
AU - Argov, Ori
AU - Weintraub, Moshe
AU - Rabinovich, Pavel
PY - 2012
Y1 - 2012
N2 - The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?
AB - The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?
UR - http://www.scopus.com/inward/record.url?scp=84866236694&partnerID=8YFLogxK
U2 - 10.1155/2012/949672
DO - 10.1155/2012/949672
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.systematicreview???
AN - SCOPUS:84866236694
SN - 2090-2824
VL - 2012
JO - International Journal of Vascular Medicine
JF - International Journal of Vascular Medicine
M1 - 949672
ER -
