The Relative Antihypertensive Potency of Propranolol, Oxprenolol, Atenolol, and Metoprolol Given Once Daily: A Double-blind, Crossover, Placebo-Controlled Study in Ambulatory Patients

Mordchai Ravid*, Ruth Lang, Izhak Jutrin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The antihypertensive effect of four β-blocking agents given once daily was compared with that of placebo in a prospective, crossover, double-blind study of 150 patients. The preparations tested were slow-release propranolol hydrochloride, 160 mg, atenolol, 100 mg, slow-release oxprenolol hydrochloride, 160 mg, and metoprolol, 200 mg. Propranolol and atenolol produced a significant decline in lying, standing, and postexercise blood pressure and pulse rate values. The effects of oxprenolol and metoprolol were not significantly different from that of placebo.

Original languageEnglish
Pages (from-to)1321-1323
Number of pages3
JournalArchives of Internal Medicine
Volume145
Issue number7
DOIs
StatePublished - Jul 1985

Fingerprint

Dive into the research topics of 'The Relative Antihypertensive Potency of Propranolol, Oxprenolol, Atenolol, and Metoprolol Given Once Daily: A Double-blind, Crossover, Placebo-Controlled Study in Ambulatory Patients'. Together they form a unique fingerprint.

Cite this