TY - JOUR
T1 - The relationship of depression, anxiety and stress with low bone mineral density in post-menopausal women
AU - Erez, Hany Burstein
AU - Weller, Aron
AU - Vaisman, Nachum
AU - Kreitler, Shulamith
N1 - Funding Information:
Acknowledgments This study supported by a grant from Myers-JDC-Brookdale Institute of Gerontology and Human Development, and Eshel, the Association for the Planning and Development of Services for the Aged in Israel.
PY - 2012/12
Y1 - 2012/12
N2 - The goal of the present study was to examine the relationships of depression, anxiety and stress with bone mineral density (BMD). We hypothesized negative relations between those mood variables and BMD in three assessed areas. The study showed association between depression and decreased BMD. The hypothesis regarding anxiety and stress was partially confirmed. Introduction: In the last decade, the relationship of osteoporosis to psychological variables has been increasingly studied. The accumulating evidence from these studies supports the conclusion that depression is related to decreased BMD. Nevertheless, several studies found no support for this relationship. Moreover, only a small number of studies examined the association between anxiety or stress and decreased BMD. The goal of the present study was to examine the relationships of depression, anxiety and stress with BMD by means of adequate measuring instruments, while controlling for background factors known to be related to BMD decrease (e.g., body mass index, family history). Method: The study included 135 post-menopausal female participants, who arrived for BMD screening, between the years 2006 and 2009. Several days prior to the examination, participants completed a series of questionnaires assessing depression and anxiety. BMD was measured using DXA, in spine, right and left hip. Results: The study showed negative associations between depression and BMD variables in the three assessed areas. There were negative correlations between anxiety, stress and spine BMD, as well as a tendency towards negative relations in the right and left hip BMD. Concurrent hierarchical regressions showed that the addition of the three psychological variables increased the explained variance by 6-8 %. In addition, depression was found to have a unique significant contribution to the explained variance in right and left hip BMD. Conclusions: The findings provide supporting evidence for the existence of associations between mood variables and decreased BMD. Further research is required for gaining deeper insight into these relationships.
AB - The goal of the present study was to examine the relationships of depression, anxiety and stress with bone mineral density (BMD). We hypothesized negative relations between those mood variables and BMD in three assessed areas. The study showed association between depression and decreased BMD. The hypothesis regarding anxiety and stress was partially confirmed. Introduction: In the last decade, the relationship of osteoporosis to psychological variables has been increasingly studied. The accumulating evidence from these studies supports the conclusion that depression is related to decreased BMD. Nevertheless, several studies found no support for this relationship. Moreover, only a small number of studies examined the association between anxiety or stress and decreased BMD. The goal of the present study was to examine the relationships of depression, anxiety and stress with BMD by means of adequate measuring instruments, while controlling for background factors known to be related to BMD decrease (e.g., body mass index, family history). Method: The study included 135 post-menopausal female participants, who arrived for BMD screening, between the years 2006 and 2009. Several days prior to the examination, participants completed a series of questionnaires assessing depression and anxiety. BMD was measured using DXA, in spine, right and left hip. Results: The study showed negative associations between depression and BMD variables in the three assessed areas. There were negative correlations between anxiety, stress and spine BMD, as well as a tendency towards negative relations in the right and left hip BMD. Concurrent hierarchical regressions showed that the addition of the three psychological variables increased the explained variance by 6-8 %. In addition, depression was found to have a unique significant contribution to the explained variance in right and left hip BMD. Conclusions: The findings provide supporting evidence for the existence of associations between mood variables and decreased BMD. Further research is required for gaining deeper insight into these relationships.
KW - Antidepressants
KW - Anxiety
KW - Bone mineral density
KW - Depression
KW - Osteoporosis
KW - Stress
UR - http://www.scopus.com/inward/record.url?scp=84876293166&partnerID=8YFLogxK
U2 - 10.1007/s11657-012-0105-0
DO - 10.1007/s11657-012-0105-0
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AN - SCOPUS:84876293166
SN - 1862-3522
VL - 7
SP - 247
EP - 255
JO - Archives of Osteoporosis
JF - Archives of Osteoporosis
IS - 1-2
ER -