The relation between latent inhibition and symptom-types in young schizophrenics

Efrat Cohen, Noam Sereni, O. Kaplan, A. Weizman, L. Kikinzon, I. Weiner, R. E. Lubow

Research output: Contribution to journalArticlepeer-review

Abstract

Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. Healthy controls exhibited the usual LI effect. LI was potentiated in schizophrenics who simultaneously exhibited high levels of negative symptoms and low levels of positive symptoms. Schizophrenic groups with other combinations of positive and negative symptoms did not differ from controls. The pattern of data suggests that past inconsistencies in the LI-schizophrenia literature may be the result of opposing processes that are associated with positive and negative symptoms.

Original languageEnglish
Pages (from-to)113-122
Number of pages10
JournalBehavioural Brain Research
Volume149
Issue number2
DOIs
StatePublished - 2 Mar 2004

Keywords

  • Attention
  • Latent inhibition
  • Negative symptoms
  • Positive symptoms
  • Schizophrenia

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