The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients

Ronit Grinbaum; Aviram Nissan; Nahum Beglaibter; Tzeela Cohen; Tamar Peretz; Herbert R. Freund

The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients

Ronit Grinbaum^*, Aviram Nissan, Nahum Beglaibter, Tzeela Cohen, Tamar Peretz, Herbert R. Freund

^*Corresponding author for this work

Hadassah University Medical Centre

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Carbohydrate antigen (CA) 19-9 is produced by adenocarcinomas of the pancreas, stomach, gall bladder, colon, ovary and lung. Serum CA 19-9 is considered the most sensitive marker for pancreatic cancer, being elevated in 75% or more of patients with pancreatic cancer. In all three cases of pancreatic cancer presented, patients died of their disease quite shortly after diagnosis. Preoperative imaging was unsuccessful in exposing the actual advanced state extent of the disease and even during surgery its real extent was underestimated. The only prognostic indicator of the observed rapid disease progression was a very significant elevation of preoperative serum CA 19-9.

Original language	English
Pages (from-to)	793-794+863
Journal	Harefuah
Volume	145
Issue number	11
State	Published - Nov 2006
Externally published	Yes

Keywords

CA-19-9 surgery
Pancreatic cancer
Survival

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Cite this

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title = "The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients",

abstract = "Carbohydrate antigen (CA) 19-9 is produced by adenocarcinomas of the pancreas, stomach, gall bladder, colon, ovary and lung. Serum CA 19-9 is considered the most sensitive marker for pancreatic cancer, being elevated in 75% or more of patients with pancreatic cancer. In all three cases of pancreatic cancer presented, patients died of their disease quite shortly after diagnosis. Preoperative imaging was unsuccessful in exposing the actual advanced state extent of the disease and even during surgery its real extent was underestimated. The only prognostic indicator of the observed rapid disease progression was a very significant elevation of preoperative serum CA 19-9.",

keywords = "CA-19-9 surgery, Pancreatic cancer, Survival",

author = "Ronit Grinbaum and Aviram Nissan and Nahum Beglaibter and Tzeela Cohen and Tamar Peretz and Freund, {Herbert R.}",

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T1 - The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients

AU - Grinbaum, Ronit

AU - Nissan, Aviram

AU - Beglaibter, Nahum

AU - Cohen, Tzeela

AU - Peretz, Tamar

AU - Freund, Herbert R.

PY - 2006/11

Y1 - 2006/11

N2 - Carbohydrate antigen (CA) 19-9 is produced by adenocarcinomas of the pancreas, stomach, gall bladder, colon, ovary and lung. Serum CA 19-9 is considered the most sensitive marker for pancreatic cancer, being elevated in 75% or more of patients with pancreatic cancer. In all three cases of pancreatic cancer presented, patients died of their disease quite shortly after diagnosis. Preoperative imaging was unsuccessful in exposing the actual advanced state extent of the disease and even during surgery its real extent was underestimated. The only prognostic indicator of the observed rapid disease progression was a very significant elevation of preoperative serum CA 19-9.

AB - Carbohydrate antigen (CA) 19-9 is produced by adenocarcinomas of the pancreas, stomach, gall bladder, colon, ovary and lung. Serum CA 19-9 is considered the most sensitive marker for pancreatic cancer, being elevated in 75% or more of patients with pancreatic cancer. In all three cases of pancreatic cancer presented, patients died of their disease quite shortly after diagnosis. Preoperative imaging was unsuccessful in exposing the actual advanced state extent of the disease and even during surgery its real extent was underestimated. The only prognostic indicator of the observed rapid disease progression was a very significant elevation of preoperative serum CA 19-9.

KW - CA-19-9 surgery

KW - Pancreatic cancer

KW - Survival

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VL - 145

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JO - Harefuah

JF - Harefuah

IS - 11

ER -

The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients

Abstract

Keywords

UN SDGs

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