TY - JOUR
T1 - The prevalence of glaucoma in patients with sleep apnea syndrome
T2 - Same as in the general population
AU - Geyer, Orna
AU - Cohen, Nahum
AU - Segev, Eitan
AU - Rath, Eitan Z.
AU - Melamud, Lina
AU - Peled, Ron
AU - Lavie, Peretz
PY - 2003/12
Y1 - 2003/12
N2 - PURPOSE: An association of glaucoma and sleep apnea syndrome (SAS) has been widely reported. We investigated the largest group of patients with SAS thus far to determine the prevalence of glaucoma among these patients. DESIGN: Cross-sectional study. METHODS: An institutional study. STUDY POPULATION: A total of 228 patients with SAS. OBSERVATION PROCEDURES: Sleep studies determined the respiratory disturbance index (RDI) during night sleep. Ocular examination included intraocular pressure (IOP) measurement, optic disk evaluation, and Humphrey visual field examination. MAIN OUTCOME MEASURES: The SAS was diagnosed as an RDI > 10. The RDI was graded to determine the severity of SAS: mild (RDI, 10-19), moderate (RDI, 20-39), and severe (RDI > 40). Open-angle glaucoma was diagnosed when a glaucomatous visual field defect matched the optic disk changes, irrespective of IOP levels. RESULTS: Nineteen participants had mild SAS (mean ± standard deviation, RDI = 15 ± 3), 129 had moderate SAS (RDI = 28 ± 5), and 80 had severe SAS (RDI = 54 ± 11). Open-angle glaucoma was found in five SAS subjects, a prevalence of 2% (95% confidence interval, 0.7% to 5%). There was no correlation between RDI and the presence of glaucoma (chi-square = 1.18; degrees of freedom = 2; P = .6) or between the RDI and the IOP (r = -0.067; P = .316). CONCLUSION: The prevalence of glaucoma in SAS patients was similar to that in the general Caucasian population.
AB - PURPOSE: An association of glaucoma and sleep apnea syndrome (SAS) has been widely reported. We investigated the largest group of patients with SAS thus far to determine the prevalence of glaucoma among these patients. DESIGN: Cross-sectional study. METHODS: An institutional study. STUDY POPULATION: A total of 228 patients with SAS. OBSERVATION PROCEDURES: Sleep studies determined the respiratory disturbance index (RDI) during night sleep. Ocular examination included intraocular pressure (IOP) measurement, optic disk evaluation, and Humphrey visual field examination. MAIN OUTCOME MEASURES: The SAS was diagnosed as an RDI > 10. The RDI was graded to determine the severity of SAS: mild (RDI, 10-19), moderate (RDI, 20-39), and severe (RDI > 40). Open-angle glaucoma was diagnosed when a glaucomatous visual field defect matched the optic disk changes, irrespective of IOP levels. RESULTS: Nineteen participants had mild SAS (mean ± standard deviation, RDI = 15 ± 3), 129 had moderate SAS (RDI = 28 ± 5), and 80 had severe SAS (RDI = 54 ± 11). Open-angle glaucoma was found in five SAS subjects, a prevalence of 2% (95% confidence interval, 0.7% to 5%). There was no correlation between RDI and the presence of glaucoma (chi-square = 1.18; degrees of freedom = 2; P = .6) or between the RDI and the IOP (r = -0.067; P = .316). CONCLUSION: The prevalence of glaucoma in SAS patients was similar to that in the general Caucasian population.
UR - http://www.scopus.com/inward/record.url?scp=0344441353&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(03)00709-8
DO - 10.1016/S0002-9394(03)00709-8
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 14644220
AN - SCOPUS:0344441353
SN - 0002-9394
VL - 136
SP - 1093
EP - 1096
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 6
ER -