The Preparation and Properties of Some Halomethylpyrimidines

Y. Ashani, S. Cohen

Research output: Contribution to journalArticlepeer-review


Halogen reactivity in various 5‐halomethylpyrimidines is ascribed to mesomeric electron transfer from the ring to the halomethyl group. In the more stable 6‐halomethylpyrimidines, electron abstraction from the ring is of an inductive nature. These effects are reflected in differences in the dissociation constants of corresponding members of the two series.

Original languageEnglish
Pages (from-to)101-105
Number of pages5
JournalIsrael Journal of Chemistry
Issue number3
StatePublished - 1965
Externally publishedYes


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