The pattern of bone disease in transfusion-dependent thalassemia major patients

K. Katz*, G. Horev, J. Goshen, H. Tamary

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Twenty-eight patients with thalassemia major were treated with frequent blood transfusions for 10-25 years. Eleven (39%) had radiographic signs of osteoporosis, and four (14%) presented with fractures. Keeping hemoglobin level above 9.0 g/dl reduced osteoporosis and the incidence of fractures but did not prevent them. Osteonecrosis of the femoral head and distal femur, not previously reported, was noted in two patients.

Original languageEnglish
Pages (from-to)577-580
Number of pages4
JournalIsrael Journal of Medical Sciences
Volume30
Issue number8
StatePublished - 1994
Externally publishedYes

Keywords

  • Bone disease
  • Fracture
  • Osteonecrosis
  • Pediatrics
  • Thalassemia major

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