Abstract
Twenty-eight patients with thalassemia major were treated with frequent blood transfusions for 10-25 years. Eleven (39%) had radiographic signs of osteoporosis, and four (14%) presented with fractures. Keeping hemoglobin level above 9.0 g/dl reduced osteoporosis and the incidence of fractures but did not prevent them. Osteonecrosis of the femoral head and distal femur, not previously reported, was noted in two patients.
| Original language | English |
|---|---|
| Pages (from-to) | 577-580 |
| Number of pages | 4 |
| Journal | Israel Journal of Medical Sciences |
| Volume | 30 |
| Issue number | 8 |
| State | Published - 1994 |
| Externally published | Yes |
Keywords
- Bone disease
- Fracture
- Osteonecrosis
- Pediatrics
- Thalassemia major