The palliative efficacy of a single high dose of radiation in treatment of symptomatic osseous metastases

Frida Barak, Abraham Werner, Natalio Walach, Yoav Horn

Research output: Contribution to journalArticlepeer-review

Abstract

Radiation therapy is effective for palliation of painful metastatic osseous lesions. Various fractionation doses have been previously described. The present study was initiated to evaluate the efficacy of a high single dose of radiation on pain relief, with the goal of reducing the number of radiation sessions to a minimum. Treatment consisted of a high single dose! of radiation ranging between 6 to 10 Gy administered to painful osseous metastases. Prior to radiation therapy response to conservative analgesic therapy was minimal inmost cases. Response to radiation therapy thereafter was 71.3% lasting up to 6 and 12 months in 37.3% and 20.9% of cases respectively.

Original languageEnglish
Pages (from-to)1233-1235
Number of pages3
JournalInternational Journal of Radiation Oncology Biology Physics
Volume13
Issue number8
DOIs
StatePublished - Aug 1987
Externally publishedYes

Keywords

  • Osseous metastases
  • Radiation
  • Single dose

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