The palliative efficacy of a single high dose of radiation in treatment of symptomatic osseous metastases

Frida Barak*, Abraham Werner, Natalio Walach, Yoav Horn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Radiation therapy is effective for palliation of painful metastatic osseous lesions. Various fractionation doses have been previously described. The present study was initiated to evaluate the efficacy of a high single dose of radiation on pain relief, with the goal of reducing the number of radiation sessions to a minimum. Treatment consisted of a high single dose! of radiation ranging between 6 to 10 Gy administered to painful osseous metastases. Prior to radiation therapy response to conservative analgesic therapy was minimal inmost cases. Response to radiation therapy thereafter was 71.3% lasting up to 6 and 12 months in 37.3% and 20.9% of cases respectively.

Original languageEnglish
Pages (from-to)1233-1235
Number of pages3
JournalInternational Journal of Radiation Oncology Biology Physics
Volume13
Issue number8
DOIs
StatePublished - Aug 1987
Externally publishedYes

Keywords

  • Osseous metastases
  • Radiation
  • Single dose

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