TY - JOUR
T1 - The outcome of preterm neonates with intraventricular hemorrhage delivered with intravenous meperidine or epidural analgesia
AU - Evron, Shmuel
AU - Ezri, Tiberiu
AU - Rigini, Nugzar
AU - Gomel, Andre
AU - Szmuk, Peter
AU - Sadan, Oscar
AU - Kohelet, David
PY - 2007/2
Y1 - 2007/2
N2 - We aimed to study, retrospectively, the neonatal outcome of 45 preterm neonates with intraventricular hemorrhage (IVH) who were delivered vaginally with intravenous meperidine (n = 23) or epidural analgesia (n = 22). Neonates in the epidural group had a better outcome in terms of a first-minute Apgar score of 7 or less, in 31% vs 69% (P = 0.001); 5-min Apgar score of 7 or less, in 18% vs 82% (P = 0.003); a lower incidence of respiratory distress syndrome (RDS; 23% vs 30%; P = 0.03); a lower dopamine requirement during the first neonatal week (13% vs 72%; P = 0.01); and a higher survival rate (91% vs 58%, respectively; P = 0.008). It is concluded that preterm neonates with IVH had a better outcome when delivered to mothers receiving epidural analgesia as compared to those receiving intravenous meperidine.
AB - We aimed to study, retrospectively, the neonatal outcome of 45 preterm neonates with intraventricular hemorrhage (IVH) who were delivered vaginally with intravenous meperidine (n = 23) or epidural analgesia (n = 22). Neonates in the epidural group had a better outcome in terms of a first-minute Apgar score of 7 or less, in 31% vs 69% (P = 0.001); 5-min Apgar score of 7 or less, in 18% vs 82% (P = 0.003); a lower incidence of respiratory distress syndrome (RDS; 23% vs 30%; P = 0.03); a lower dopamine requirement during the first neonatal week (13% vs 72%; P = 0.01); and a higher survival rate (91% vs 58%, respectively; P = 0.008). It is concluded that preterm neonates with IVH had a better outcome when delivered to mothers receiving epidural analgesia as compared to those receiving intravenous meperidine.
KW - Analgesia in labor
KW - Intraventricular hemorrhage
KW - Neonatal complications
KW - Perinatal labor
UR - http://www.scopus.com/inward/record.url?scp=33947644310&partnerID=8YFLogxK
U2 - 10.1007/s00540-006-0461-2
DO - 10.1007/s00540-006-0461-2
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AN - SCOPUS:33947644310
SN - 0913-8668
VL - 21
SP - 90
EP - 93
JO - Journal of Anesthesia
JF - Journal of Anesthesia
IS - 1
ER -