TY - JOUR
T1 - The origin and significance of anti-DNA antibodies
AU - Isenberg, David
AU - Shoenfeld, Yehuda
N1 - Funding Information:
The Bloomsbury Rheumatology Department, University College and The Middlesex Hospital Medical School, London, UK and The Department of Internal Medicine D and Research Units of Autoimmune Diseases, Soroka Medical Center, Faculty of Health Sciences, Ben Gurion Universityo f the Negev, BeerS heva, Israel.
PY - 1987
Y1 - 1987
N2 - Polyreactive autoantibodies able to bind double-stranded DNA are a characteristic of systemic lucus erytheamtosus. Here, David Isenberg and Yehuda Shoenfeld discuss the likelihood that DNA is the immunogen in this disorder, and review a number of cross-reactions that may underline the detection of the antibodies.
AB - Polyreactive autoantibodies able to bind double-stranded DNA are a characteristic of systemic lucus erytheamtosus. Here, David Isenberg and Yehuda Shoenfeld discuss the likelihood that DNA is the immunogen in this disorder, and review a number of cross-reactions that may underline the detection of the antibodies.
UR - http://www.scopus.com/inward/record.url?scp=45949129007&partnerID=8YFLogxK
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AN - SCOPUS:45949129007
VL - 8
SP - XIII
JO - Trends in Immunology
JF - Trends in Immunology
SN - 1471-4906
IS - 9
ER -