The origin and significance of anti-DNA antibodies

David Isenberg, Yehuda Shoenfeld

Research output: Contribution to journalReview articlepeer-review


Polyreactive autoantibodies able to bind double-stranded DNA are a characteristic of systemic lucus erytheamtosus. Here, David Isenberg and Yehuda Shoenfeld discuss the likelihood that DNA is the immunogen in this disorder, and review a number of cross-reactions that may underline the detection of the antibodies.

Original languageEnglish
Pages (from-to)XIII
JournalImmunology Today
Issue number9
StatePublished - 1987
Externally publishedYes


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