The no-reflow phenomenon following percutaneous coronary intervention

Shmuel Schwartzenberg, Amir Halkin, Ariel Finkelstein, Gad Keren, Shmuel Banai

Research output: Contribution to journalReview articlepeer-review


The no-reflow phenomenon after successful coronary artery perfusion is caused by a myocardial perfusion defect due to impaired blood flow in the microvascular bed. This phenomenon is more prevalent among acute myocardial infarction patients who have additional cardiovascular risk factors, and its presence constitutes an independent negative prognostic sign. The impaired microvascular myocardial blood flow is caused by microemboli and by intracellular processes taking place during the reperfusion phase. In the last few years, many studies have been published regarding new diagnostic and treatment modalities based on a better understanding of the pathophysiological processes implicated.

Original languageEnglish
Pages (from-to)381-385
Number of pages5
Issue number6
StatePublished - Jun 2009
Externally publishedYes


  • Microvascular injury
  • No-reflow phenomenon
  • Percutaneous coronary intervention
  • Reperfusion injury
  • ST-elevation myocardial infarction


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