TY - JOUR
T1 - The no-reflow phenomenon following percutaneous coronary intervention
AU - Schwartzenberg, Shmuel
AU - Halkin, Amir
AU - Finkelstein, Ariel
AU - Keren, Gad
AU - Banai, Shmuel
PY - 2009/6
Y1 - 2009/6
N2 - The no-reflow phenomenon after successful coronary artery perfusion is caused by a myocardial perfusion defect due to impaired blood flow in the microvascular bed. This phenomenon is more prevalent among acute myocardial infarction patients who have additional cardiovascular risk factors, and its presence constitutes an independent negative prognostic sign. The impaired microvascular myocardial blood flow is caused by microemboli and by intracellular processes taking place during the reperfusion phase. In the last few years, many studies have been published regarding new diagnostic and treatment modalities based on a better understanding of the pathophysiological processes implicated.
AB - The no-reflow phenomenon after successful coronary artery perfusion is caused by a myocardial perfusion defect due to impaired blood flow in the microvascular bed. This phenomenon is more prevalent among acute myocardial infarction patients who have additional cardiovascular risk factors, and its presence constitutes an independent negative prognostic sign. The impaired microvascular myocardial blood flow is caused by microemboli and by intracellular processes taking place during the reperfusion phase. In the last few years, many studies have been published regarding new diagnostic and treatment modalities based on a better understanding of the pathophysiological processes implicated.
KW - Microvascular injury
KW - No-reflow phenomenon
KW - Percutaneous coronary intervention
KW - Reperfusion injury
KW - ST-elevation myocardial infarction
UR - http://www.scopus.com/inward/record.url?scp=72249104880&partnerID=8YFLogxK
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AN - SCOPUS:72249104880
SN - 0017-7768
VL - 148
SP - 381
EP - 385
JO - Harefuah
JF - Harefuah
IS - 6
ER -
