TY - JOUR
T1 - The neuroleptic malignant syndrome
T2 - agent and host interaction
AU - Shalev, A.
AU - Munitz, H.
PY - 1986/4
Y1 - 1986/4
N2 - ABSTRACT This review comprises an exhaustive analysis of 120 case reports of neuroleptic malignant syndrome (NMS) representing the majority of published clinical data on this syndrome. Epidemiological, clinical and biological parameters, as well as those concerning the agent and the treatment of the syndrome, are critically evaluated on the basis of this data. The rate of neuroleptic loading is shown to play a cardinal role in the development of NMS. Rechallenge and aftercare of patients who need anti‐psychotic treatment after NMS are considered.
AB - ABSTRACT This review comprises an exhaustive analysis of 120 case reports of neuroleptic malignant syndrome (NMS) representing the majority of published clinical data on this syndrome. Epidemiological, clinical and biological parameters, as well as those concerning the agent and the treatment of the syndrome, are critically evaluated on the basis of this data. The rate of neuroleptic loading is shown to play a cardinal role in the development of NMS. Rechallenge and aftercare of patients who need anti‐psychotic treatment after NMS are considered.
KW - Neuroleptic malignant syndrome
KW - adverse drug reaction
KW - major side effects
KW - tranquilizers
UR - http://www.scopus.com/inward/record.url?scp=0022469535&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0447.1986.tb02694.x
DO - 10.1111/j.1600-0447.1986.tb02694.x
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C2 - 2873715
AN - SCOPUS:0022469535
SN - 0001-690X
VL - 73
SP - 337
EP - 347
JO - Acta Psychiatrica Scandinavica
JF - Acta Psychiatrica Scandinavica
IS - 4
ER -
