TY - JOUR
T1 - The neurocognitive outcome of IUGR children born to mothers with and without preeclampsia
AU - Leitner, Y.
AU - Harel, S.
AU - Geva, R.
AU - Eshel, R.
AU - Yaffo, A.
AU - Many, A.
PY - 2012/11
Y1 - 2012/11
N2 - Objective: To examine long-term behavioral and neurodevelopmental outcome of children born growth restricted and exposed to hypertension in utero at 9 years of age. Methods: Somatic growth and neurocognitive outcomes were evaluated at age 910 years of age in 42 children born with intra uterine growth restriction (IUGR) after pregnancies complicated by hypertensive disorder (17 with maternal preeclampsia and 25 after gestational hypertension). This study group was compared to a control group of 78 IUGR children born after normotensive pregnancy. Results: Only weight was found to be significantly lower in the hypertensive-IUGR group, versus the normotensive IUGR children. No significant differences were found in any of the neurocognitive parameters including IQ, school achievements, and neurodevelopmental score at age 910 years. Conclusion: IUGR is a well known risk factor for later cognitive difficulties but maternal hypertensive disorder does not seem to add significantly to this risk.
AB - Objective: To examine long-term behavioral and neurodevelopmental outcome of children born growth restricted and exposed to hypertension in utero at 9 years of age. Methods: Somatic growth and neurocognitive outcomes were evaluated at age 910 years of age in 42 children born with intra uterine growth restriction (IUGR) after pregnancies complicated by hypertensive disorder (17 with maternal preeclampsia and 25 after gestational hypertension). This study group was compared to a control group of 78 IUGR children born after normotensive pregnancy. Results: Only weight was found to be significantly lower in the hypertensive-IUGR group, versus the normotensive IUGR children. No significant differences were found in any of the neurocognitive parameters including IQ, school achievements, and neurodevelopmental score at age 910 years. Conclusion: IUGR is a well known risk factor for later cognitive difficulties but maternal hypertensive disorder does not seem to add significantly to this risk.
KW - IUGR
KW - Neurodevelopmental outcome
KW - Preeclampsia
UR - http://www.scopus.com/inward/record.url?scp=84867553730&partnerID=8YFLogxK
U2 - 10.3109/14767058.2012.684164
DO - 10.3109/14767058.2012.684164
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C2 - 22524188
AN - SCOPUS:84867553730
SN - 1476-7058
VL - 25
SP - 2206
EP - 2208
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
IS - 11
ER -