The major histocompatibility complex and inflammation

Arnon Blum*, Hylton Miller

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The major histocompatibility complex (MHC) is of major medical interest because of its contribution to transplant rejection and to variation among individuals in susceptibility to a variety of autoimmune disorders. In addition to its role in influencing the propensity for known autoimmune diseases, the MHC contains genes contributing to several other hereditary disorders that are not autoimmune in nature or in which the role of autoimmunity is uncertain. Recently, a duster of genes encoding inflammation- related proteins were found, and our review focuses on these findings and their clinical relevance.

Original languageEnglish
Pages (from-to)169-172
Number of pages4
JournalSouthern Medical Journal
Volume93
Issue number2
DOIs
StatePublished - Feb 2000

Fingerprint

Dive into the research topics of 'The major histocompatibility complex and inflammation'. Together they form a unique fingerprint.

Cite this