TY - JOUR
T1 - The maccabi glaucoma study
T2 - Prevalence and incidence of glaucoma in a large Israeli health maintenance organization
AU - Levkovitch-Verbin, Hani
AU - Goldshtein, Inbal
AU - Chodick, Gabriel
AU - Zigman, Nir
AU - Shalev, Varda
N1 - Funding Information:
All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported. The authors indicate the following funding support: unrestricted grants from Pfizer LTD , Herzlia, Israel; Tradis Gat , Tel-Aviv, Israel; and MSD , Tel-Aviv, Israel. None of these sponsors or funding organization had any role in the design or conduct of this research. Contributions of authors: design and conduct of the study (H.L.-V., I.G., G.C.); collection (H.L.-V., I.G., N.Z.), management (H.L.-V., I.G., G.C., V.S.), analysis (H.L.-V., I.G., G.C.); interpretation of the data (H.L.-V., I.G., G.C.); and preparation, review, and approval of the manuscript (H.L.-V., I.G., G.C., V.S.).
PY - 2014/8
Y1 - 2014/8
N2 - Purpose To investigate the prevalence and incidence of glaucoma in a large health maintenance organization (HMO) in Israel. Design A population-based retrospective cohort study, conducted using electronic medical database. Methods Collected data included personal and medical characteristics. setting: Maccabi Healthcare Services, the second-largest HMO in Israel, insuring 2 million members and serving 25% of the population with a nationwide distribution. study population: Maccabi members from January 2003 to December 2010. main outcome measures: Prevalence and incidence of glaucoma according to the International Classification of Diseases, 9th revision, Clinical Modification diagnostic codes. Results A total of 15 708 prevalent glaucoma patients were identified among active members of Maccabi in December 2010. A total of 15 332 (97.6%) were 40 years or older, with a point prevalence of 2.2%. Prevalence of glaucoma was strongly associated with age, ranging from 0.28% at age 40-50 to 9.2% among elderly aged 80 or above. The 5 most prevalent diagnoses were open-angle glaucoma (1.61%), exfoliation glaucoma (0.20%), unspecified glaucoma (0.17%), angle closure (0.11%), and normal tension glaucoma (0.06%). We identified 6674 incident glaucoma patients diagnosed between 2003 and 2010. The observed incidence density rate among 40+-year-old members was 1.84 (1.79-1.88) new cases per 1000 person-years. Median age at diagnosis was 64 years old. The risk of glaucoma was similar between sexes up to age 70 years, and was significantly (P <.01) higher in men in older ages. Conclusions Glaucoma affects nearly 10% of the elderly population in Maccabi, with the highest risk of diagnosis at age 70-74. Since glaucoma leads to irreversible vision loss, the present estimates of morbidity should be of significant concern.
AB - Purpose To investigate the prevalence and incidence of glaucoma in a large health maintenance organization (HMO) in Israel. Design A population-based retrospective cohort study, conducted using electronic medical database. Methods Collected data included personal and medical characteristics. setting: Maccabi Healthcare Services, the second-largest HMO in Israel, insuring 2 million members and serving 25% of the population with a nationwide distribution. study population: Maccabi members from January 2003 to December 2010. main outcome measures: Prevalence and incidence of glaucoma according to the International Classification of Diseases, 9th revision, Clinical Modification diagnostic codes. Results A total of 15 708 prevalent glaucoma patients were identified among active members of Maccabi in December 2010. A total of 15 332 (97.6%) were 40 years or older, with a point prevalence of 2.2%. Prevalence of glaucoma was strongly associated with age, ranging from 0.28% at age 40-50 to 9.2% among elderly aged 80 or above. The 5 most prevalent diagnoses were open-angle glaucoma (1.61%), exfoliation glaucoma (0.20%), unspecified glaucoma (0.17%), angle closure (0.11%), and normal tension glaucoma (0.06%). We identified 6674 incident glaucoma patients diagnosed between 2003 and 2010. The observed incidence density rate among 40+-year-old members was 1.84 (1.79-1.88) new cases per 1000 person-years. Median age at diagnosis was 64 years old. The risk of glaucoma was similar between sexes up to age 70 years, and was significantly (P <.01) higher in men in older ages. Conclusions Glaucoma affects nearly 10% of the elderly population in Maccabi, with the highest risk of diagnosis at age 70-74. Since glaucoma leads to irreversible vision loss, the present estimates of morbidity should be of significant concern.
UR - http://www.scopus.com/inward/record.url?scp=84905091200&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2014.04.026
DO - 10.1016/j.ajo.2014.04.026
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C2 - 24794285
AN - SCOPUS:84905091200
SN - 0002-9394
VL - 158
SP - 402-408.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 2
ER -