The lymphoproliferative disease virus of turkeys represents a distinct class of avian type-C retrovirus

Ayelet Chajut; Ronit Sarid; Abraham Yaniv; Gary W. Smythers; Steven R. Tronick; Arnona Gazit

doi:10.1016/0378-1119(92)90225-E

The lymphoproliferative disease virus of turkeys represents a distinct class of avian type-C retrovirus

Ayelet Chajut
, Ronit Sarid
, Abraham Yaniv
, Gary W. Smythers
, Steven R. Tronick
, Arnona Gazit^*

^*Corresponding author for this work

Clinical Microbiology and Immunology

Tel Aviv University
National Institutes of Health

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The lymphoproliferative disease virus of turkeys (LPDV) is the etiological agent of a rapidly developing lymphoproliferative process in turkeys. To better understand the genetic relationships of LPDV to other retroviruses we determined the nucleotide sequence of its pol gene. Comparative computer analyses of the deduced amino acid sequences of the reverse transcriptase and integrase domains within pol established that LPDV represents a distinct class of avian retroviruses that is most closely related to the avian leukemia-sarcoma viruses.

Original language	English
Pages (from-to)	349-354
Number of pages	6
Journal	Gene
Volume	122
Issue number	2
DOIs	https://doi.org/10.1016/0378-1119(92)90225-E
State	Published - 15 Dec 1992

Funding

Funders
Fund for Basic Research
Israel Cancer Research Fund
Israel Academy of Sciences and Humanities
Israel Cancer Association

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Recombinant DNA
genetic relatedness
integrase
pol
reverse transcriptase

Access to Document

10.1016/0378-1119(92)90225-E

Cite this

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title = "The lymphoproliferative disease virus of turkeys represents a distinct class of avian type-C retrovirus",

abstract = "The lymphoproliferative disease virus of turkeys (LPDV) is the etiological agent of a rapidly developing lymphoproliferative process in turkeys. To better understand the genetic relationships of LPDV to other retroviruses we determined the nucleotide sequence of its pol gene. Comparative computer analyses of the deduced amino acid sequences of the reverse transcriptase and integrase domains within pol established that LPDV represents a distinct class of avian retroviruses that is most closely related to the avian leukemia-sarcoma viruses.",

keywords = "Recombinant DNA, genetic relatedness, integrase, pol, reverse transcriptase",

author = "Ayelet Chajut and Ronit Sarid and Abraham Yaniv and Smythers, \{Gary W.\} and Tronick, \{Steven R.\} and Arnona Gazit",

note = "Funding Information: We thank Dr. S.A. Aaronson for his continued support and encouragement.T his study was supported in part by a project grant from the Fund for Basic Research administered by the Israel Academy of Sciences and Humanities, the Israel Cancer Research Fund and the Israel Cancer Association.",

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doi = "10.1016/0378-1119(92)90225-E",

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AU - Chajut, Ayelet

AU - Sarid, Ronit

AU - Yaniv, Abraham

AU - Smythers, Gary W.

AU - Tronick, Steven R.

AU - Gazit, Arnona

N1 - Funding Information: We thank Dr. S.A. Aaronson for his continued support and encouragement.T his study was supported in part by a project grant from the Fund for Basic Research administered by the Israel Academy of Sciences and Humanities, the Israel Cancer Research Fund and the Israel Cancer Association.

PY - 1992/12/15

Y1 - 1992/12/15

N2 - The lymphoproliferative disease virus of turkeys (LPDV) is the etiological agent of a rapidly developing lymphoproliferative process in turkeys. To better understand the genetic relationships of LPDV to other retroviruses we determined the nucleotide sequence of its pol gene. Comparative computer analyses of the deduced amino acid sequences of the reverse transcriptase and integrase domains within pol established that LPDV represents a distinct class of avian retroviruses that is most closely related to the avian leukemia-sarcoma viruses.

AB - The lymphoproliferative disease virus of turkeys (LPDV) is the etiological agent of a rapidly developing lymphoproliferative process in turkeys. To better understand the genetic relationships of LPDV to other retroviruses we determined the nucleotide sequence of its pol gene. Comparative computer analyses of the deduced amino acid sequences of the reverse transcriptase and integrase domains within pol established that LPDV represents a distinct class of avian retroviruses that is most closely related to the avian leukemia-sarcoma viruses.

KW - Recombinant DNA

KW - genetic relatedness

KW - integrase

KW - pol

KW - reverse transcriptase

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The lymphoproliferative disease virus of turkeys represents a distinct class of avian type-C retrovirus

Abstract

Funding

UN SDGs

Keywords

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