Abstract
Notch signaling is adjusted to different physiological contexts by expression patterns of Notch ligands and receptors, as well as by posttranslational modifications that modulate the ligand/receptor affinity. In this issue of The EMBO Journal, Suckling et al (2017) show that an interaction of Notch ligands with membrane lipids promotes Notch binding and activation, thus proposing a new mode of Notch activity regulation.
Original language | English |
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Pages (from-to) | 2182-2183 |
Number of pages | 2 |
Journal | EMBO Journal |
Volume | 36 |
Issue number | 15 |
DOIs | |
State | Published - 1 Aug 2017 |