The leukergy test in patients with ischemic heart disease

Shlomo Berliner, Samuel Sclarovsky, Gad Lavie, Jack Pinkhas, Moshe Aronson, Jacob Agmon*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In search of a simple method for potential evaluation of leukocyte aggregation in states of infarction, we compared the leukergy test, which consists of leukocyte aggregation visualized in a peripheral blood test, to the neutrophil aggregation activity (NAA) test, which consists of in vitro aggregation of neutrophils from normal donors by a patient's plasma. Seventy-five patients participated in the study; 20 with ischemic heart disease and no infarction, 41 with relatively small myocardial infarctions, and 14 with large myocardial infarctions, the respective values of leukergy being 6.9 ± 3.2, 10.8 ± 4.6, and 20.5 ± 14%. On the other hand, neutrophil aggregation activity was the same in a group of 10 patients without myocardial infarction and 10 with myocardial infarction. In these two groups, which showed no difference in the NAA test, the respective leukergy values were 4 ± 1.5 and 21.7 ± 10.6%. Thus leukergy correlates better with the clinical picture than does the NAA test.

Original languageEnglish
Pages (from-to)19-22
Number of pages4
JournalAmerican Heart Journal
Volume111
Issue number1
DOIs
StatePublished - Jan 1986

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