The Koebner phenomenon

Lior Sagi, Henri Trau

Research output: Contribution to journalArticlepeer-review

Abstract

The Koebner phenomenon is one of the most well-known entities in dermatology. It was first described by Heinrich Koebner in 1876 as the formation of psoriatic lesions in uninvolved skin of psoriatic patients after cutaneous trauma. This isomorphic phenomenon is now known to involve numerous diseases, among them vitiligo, lichen planus, and Darier disease. The pathogenesis of the Koebner phenomenon is still obscure but may involve cytokines, stress proteins, adhesion molecules, and autoantigens. This contribution reviews the clinical manifestations of Koebner phenomenon, its provocative factors, suggested pathogenesis mechanisms, and the various skin conditions that exhibit this unique response.

Original languageEnglish
Pages (from-to)231-236
Number of pages6
JournalClinics in Dermatology
Volume29
Issue number2
DOIs
StatePublished - Mar 2011
Externally publishedYes

Fingerprint

Dive into the research topics of 'The Koebner phenomenon'. Together they form a unique fingerprint.

Cite this