Abstract
The INTEROCC study, an international case-control study of brain cancer conducted in seven countries, was conducted to evaluated whether risk of meningioma is associated with several occupational exposures. A job exposure matrix was employed to derive estimates of exposure for various agents, including asbestos, benzo(a)pyrene, bitumen, diesel and gasoline engine exhaust, formaldehyde, oil mist, PAH, and SO2. Most agents examined did not provoke excess risks of meningioma. Occupational exposure to mineral oil appeared to be associated with elevated risk of meningioma. Among women, there was also some indication of exposure-response for asbestos and some indication of excess risks from formaldehyde in the highest exposure categories. No association was observed with other occupational substances investigated, which included combustion products, mineral and organic dusts, and other chemical agents.
Original language | English |
---|---|
Pages (from-to) | 12-22 |
Number of pages | 11 |
Journal | Occupational and Environmental Medicine |
Volume | 75 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2018 |
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The INTEROCC case-control study : Risk of meningioma and occupational exposure to selected combustion products, dusts and other chemical agents. / McElvenny, Damien M.; Van Tongeren, Martie; Turner, Michelle C. et al.
In: Occupational and Environmental Medicine, Vol. 75, No. 1, 01.2018, p. 12-22.Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - The INTEROCC case-control study
T2 - Risk of meningioma and occupational exposure to selected combustion products, dusts and other chemical agents
AU - McElvenny, Damien M.
AU - Van Tongeren, Martie
AU - Turner, Michelle C.
AU - Benke, Geza
AU - Figuerola, Jordi
AU - Fleming, Sarah
AU - Hours, Martine
AU - Kincl, Laurel
AU - Krewski, Daniel
AU - McLean, Dave
AU - Parent, Marie Élise
AU - Richardson, Lesley
AU - Schlehofer, Brigitte
AU - Schlaefer, Klaus
AU - Sadetzki, Siegal
AU - Schüz, Joachim
AU - Siemiatycki, Jack
AU - Cardis, Elisabeth
N1 - Funding Information: Funding Mct was funded by a government of canada Banting Postdoctoral Fellowship. the interOcc study was funded by the national institutes for Health (niH) grant no. 1r01ca124759 (Pi e cardis). coding of the French occupational data was in part funded by aFSSet (convention n° St-2005-004). the interPHOne study was supported by funding from the european Fifth Framework Programme, ’Quality of life and Management of living resources’ (contract 100 QlK4-ct-1999901563) and the international Union against cancer (Uicc). the Uicc received funds for this purpose from the Mobile Manufacturers’ Forum and gSM association. in australia, funding was received from the australian national Health and Medical research council (eMe grant 219129) with funds originally derived from mobile phone service license fees; the University of Sydney Medical Foundation Programme; the cancer council nSW and the cancer council Victoria. in canada, funding was received from the canadian institutes of Health research (project MOP-42525); the canada research chair programme; the guzzo-crS chair in environment and cancer; the Fonds de la recherche en santé duQuébec; the canadian institutes of Health research (ciHr), the latter including partial support from the canadian Wireless telecommunications association; the nSerc chair in risk Science at the University of Ottawa. in France, funding was received by l’association pour la recherche sur le cancer (arc) (contrat n85142) and three network operators (Orange, SFr, Bouygues telecom). in germany, funding was received from the german Mobile Phone research Programme (Deutsches Mobilfunkforschungsprogramm) of the german Federal Ministry for the environment, nuclear Safety, and nature Protection; the Ministry for the environment and traffic of the state of Baden-Wuerttemberg; the Ministry for the environment of the state of north rhine-Westphalia; the MaiFOr Programme (Mainzer Forschungsforderungsprogramm) of the University of Mainz. in new Zealand, funding was provided by the Health research council, Hawke’s Bay Medical research Foundation, the Wellington Medical research Foundation, the Waikato Medical research Foundation and the cancer Society of new Zealand. additional funding for the UK study was received from the Mobile telecommunications, Health and research (MtHr) programme, funding from the Health and Safety executive, the Department of Health, the UK network Operators (O2, Orange, t-Mobile, Vodafone, ’3’) and the Scottish executive. all industry funding was governed by contracts guaranteeing the complete scientific independence of the investigators. Funding Information: MCT was funded by a Government of Canada Banting Postdoctoral Fellowship. The INTEROCC study was funded by the National Institutes for Health (NIH) Grant No. 1R01CA124759 (PI E Cardis). Coding of the French occupational data was in part funded by AFSSET (Convention N° ST-2005-004). The INTERPHONE study was supported by funding from the European Fifth Framework Programme, 'Quality of Life and Management of Living Resources' (contract 100 QLK4-CT-1999901563) and the International Union against Cancer (UICC). The UICC received funds for this purpose from the Mobile Manufacturers' Forum and GSM Association. In Australia, funding was received from the Australian National Health and Medical Research Council (EME Grant 219129) with funds originally derived from mobile phone service license fees; the University of Sydney Medical Foundation Programme; the Cancer Council NSW and the Cancer Council Victoria. In Canada, funding was received from the Canadian Institutes of Health Research (project MOP-42525); the Canada Research Chair programme; the Guzzo-CRS Chair in Environment and Cancer; the Fonds de la recherche en santé duQuébec; the Canadian Institutes of Health Research (CIHR), the latter including partial support from the Canadian Wireless Telecommunications Association; the NSERC Chair in Risk Science at the University of Ottawa. In France, funding was received by l'Association pour la Recherche sur le Cancer (ARC) (Contrat N85142) and three network operators (Orange, SFR, Bouygues Telecom). In Germany, funding was received from the German Mobile Phone Research Programme (Deutsches Mobilfunkforschungsprogramm) of the German Federal Ministry for the Environment, Nuclear Safety, and Nature Protection; the Ministry for the Environment and Traffic of the state of Baden-Wuerttemberg; the Ministry for the Environment of the state of North Rhine-Westphalia; the MAIFOR Programme (Mainzer Forschungsforderungsprogramm) of the University of Mainz. In New Zealand, funding was provided by the Health Research Council, Hawke's Bay Medical Research Foundation, the Wellington Medical Research Foundation, the Waikato Medical Research Foundation and the Cancer Society of New Zealand. Additional funding for the UK study was received from the Mobile Telecommunications, Health and Research (MTHR) programme, funding from the Health and Safety Executive, the Department of Health, the UK Network Operators (O2, Orange, T-Mobile, Vodafone, '3') and the Scottish Executive. All industry funding was governed by contracts guaranteeing the complete scientific independence of the investigators.
PY - 2018/1
Y1 - 2018/1
N2 - The INTEROCC study, an international case-control study of brain cancer conducted in seven countries, was conducted to evaluated whether risk of meningioma is associated with several occupational exposures. A job exposure matrix was employed to derive estimates of exposure for various agents, including asbestos, benzo(a)pyrene, bitumen, diesel and gasoline engine exhaust, formaldehyde, oil mist, PAH, and SO2. Most agents examined did not provoke excess risks of meningioma. Occupational exposure to mineral oil appeared to be associated with elevated risk of meningioma. Among women, there was also some indication of exposure-response for asbestos and some indication of excess risks from formaldehyde in the highest exposure categories. No association was observed with other occupational substances investigated, which included combustion products, mineral and organic dusts, and other chemical agents.
AB - The INTEROCC study, an international case-control study of brain cancer conducted in seven countries, was conducted to evaluated whether risk of meningioma is associated with several occupational exposures. A job exposure matrix was employed to derive estimates of exposure for various agents, including asbestos, benzo(a)pyrene, bitumen, diesel and gasoline engine exhaust, formaldehyde, oil mist, PAH, and SO2. Most agents examined did not provoke excess risks of meningioma. Occupational exposure to mineral oil appeared to be associated with elevated risk of meningioma. Among women, there was also some indication of exposure-response for asbestos and some indication of excess risks from formaldehyde in the highest exposure categories. No association was observed with other occupational substances investigated, which included combustion products, mineral and organic dusts, and other chemical agents.
UR - http://www.scopus.com/inward/record.url?scp=85039057744&partnerID=8YFLogxK
U2 - 10.1136/oemed-2016-104280
DO - 10.1136/oemed-2016-104280
M3 - מאמר
C2 - 28947494
AN - SCOPUS:85039057744
VL - 75
SP - 12
EP - 22
JO - Occupational and Environmental Medicine
JF - Occupational and Environmental Medicine
SN - 1351-0711
IS - 1
ER -