TY - JOUR
T1 - The Inheritance of Gilles de la Tourette's Syndrome
AU - Eldridge, Roswell
AU - Denckla, Martha B.
AU - Hermesh, Haggai
AU - Atzenberg, Dov
AU - Lapidot, Margo
AU - Munitz, Hanan
AU - Pauls, David L.
AU - Leckman, James F.
PY - 1987/5/21
Y1 - 1987/5/21
N2 - To the Editor: Pauls and Leckman conclude that Gilles de la Tourette's syndrome, as defined by them, is inherited as an autosomal dominant trait (Oct. 16 issue).1 On the basis of this conclusion, they indicate that “the next step in understanding the genetics of Tourette's syndrome will be to try to establish a linkage relation between a marker and the hypothetical gene for the disease.” We would like to repeat a note of caution2 before the race for the hypothetical gene is joined by all other interested parties. A major unresolved issue, particularly in family studies, concerns the definition of…
AB - To the Editor: Pauls and Leckman conclude that Gilles de la Tourette's syndrome, as defined by them, is inherited as an autosomal dominant trait (Oct. 16 issue).1 On the basis of this conclusion, they indicate that “the next step in understanding the genetics of Tourette's syndrome will be to try to establish a linkage relation between a marker and the hypothetical gene for the disease.” We would like to repeat a note of caution2 before the race for the hypothetical gene is joined by all other interested parties. A major unresolved issue, particularly in family studies, concerns the definition of…
UR - http://www.scopus.com/inward/record.url?scp=0023661678&partnerID=8YFLogxK
U2 - 10.1056/NEJM198705213162116
DO - 10.1056/NEJM198705213162116
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AN - SCOPUS:0023661678
SN - 0028-4793
VL - 316
SP - 1346
EP - 1348
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 21
ER -