The Increasing Penicillin Resistance of Streptococcus pneumoniae in Central Israel from 1988 to 2002

Gilat Livni; Shai Ashkenazi; Bruria Lev; Shula Harari; Zmira Samra

The Increasing Penicillin Resistance of Streptococcus pneumoniae in Central Israel from 1988 to 2002

Gilat Livni, Shai Ashkenazi^*, Bruria Lev, Shula Harari, Zmira Samra

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Antibiotic resistance of Streptococcus pneumoniae is increasing worldwide, creating a major problem in treating pediatric infections. The aims of the present study were to study in depth current resistance rates to penicillin of S. pneumoniae in central Israel, with comparison to previous years. Overall resistance by disk diffusion increased steadily from 20.8% in 1988-1991 to 46. 0% in 2000-2002 (p=0.019). By E-test, comparison of minimal inhibitory concentrations between 1995-1996 and 2000-2002 showed a steady increase, with levels of ≥2 mcg/ml detected only since 2001. These patterns should be considered when starting empiric therapy.

Original language	English
Pages (from-to)	20-23
Number of pages	4
Journal	International Pediatrics
Volume	19
Issue number	1
State	Published - 2004
Externally published	Yes

Keywords

Israel
Penicillin
Streptococcus pneumoniae

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "Antibiotic resistance of Streptococcus pneumoniae is increasing worldwide, creating a major problem in treating pediatric infections. The aims of the present study were to study in depth current resistance rates to penicillin of S. pneumoniae in central Israel, with comparison to previous years. Overall resistance by disk diffusion increased steadily from 20.8% in 1988-1991 to 46. 0% in 2000-2002 (p=0.019). By E-test, comparison of minimal inhibitory concentrations between 1995-1996 and 2000-2002 showed a steady increase, with levels of ≥2 mcg/ml detected only since 2001. These patterns should be considered when starting empiric therapy.",

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AU - Livni, Gilat

AU - Ashkenazi, Shai

AU - Lev, Bruria

AU - Harari, Shula

AU - Samra, Zmira

PY - 2004

Y1 - 2004

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AB - Antibiotic resistance of Streptococcus pneumoniae is increasing worldwide, creating a major problem in treating pediatric infections. The aims of the present study were to study in depth current resistance rates to penicillin of S. pneumoniae in central Israel, with comparison to previous years. Overall resistance by disk diffusion increased steadily from 20.8% in 1988-1991 to 46. 0% in 2000-2002 (p=0.019). By E-test, comparison of minimal inhibitory concentrations between 1995-1996 and 2000-2002 showed a steady increase, with levels of ≥2 mcg/ml detected only since 2001. These patterns should be considered when starting empiric therapy.

KW - Israel

KW - Penicillin

KW - Streptococcus pneumoniae

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JO - International Pediatrics

JF - International Pediatrics

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The Increasing Penicillin Resistance of Streptococcus pneumoniae in Central Israel from 1988 to 2002

Abstract

Keywords

UN SDGs

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