TY - JOUR
T1 - The impact of the Impeller's hub design on the performance and blood damage in a microaxial mechanical circulatory support device – A numerical study
AU - Gabso, Yuval
AU - Rosenfeld, Moshe
AU - Avrahami, Idit
N1 - Publisher Copyright:
© 2024 Elsevier Ltd
PY - 2024/9
Y1 - 2024/9
N2 - This study uses CFD methods to investigate the effects of the impeller's geometry on the hemodynamic characteristics, pump performance, and blood damage parameters, in a percutaneous microaxial Mechanical Circulatory Support (MCS) device. The numerical simulations employ the steady state Reynolds-Averaged Navier-Stokes approximation using the SST k−ω turbulent model. Three different impeller models are examined with different hub conversion angles (α = 0○, 3○ and 5○). The analysis includes 23 cases for different pressure heads (Δp = 60–80 mmHg) and angular velocities (ω = 30–52 kRPM). The obtained flow rate is compared between the cases to assess the effect of the impeller's design and working conditions on the pump performance. The comparative risk of shear-induced platelet activation is estimated using the statistical median of the stress-accumulation values calculated along streamlines. The risk of hemolysis is estimated using the average exposure time to shear stress above a threshold (τ > 425 Pa). The results reveal that the shape of the impeller's hub has a great impact on the flow patterns, performance, and risk of blood damage, as well as the angular velocity. The highest flow rate (Q = 3.7 L/min) and efficiency (η = 11.3 %) were achieved using a straight hub (α = 0○). Similarly, for the same condition of flow and pressure, the straight hub impeller has the lowest blood damage risk parameters. This study shed light on the effect of pump design on the performance and risk of blood damage, indicating the roles of the hub shape and angular velocity as dominant parameters.
AB - This study uses CFD methods to investigate the effects of the impeller's geometry on the hemodynamic characteristics, pump performance, and blood damage parameters, in a percutaneous microaxial Mechanical Circulatory Support (MCS) device. The numerical simulations employ the steady state Reynolds-Averaged Navier-Stokes approximation using the SST k−ω turbulent model. Three different impeller models are examined with different hub conversion angles (α = 0○, 3○ and 5○). The analysis includes 23 cases for different pressure heads (Δp = 60–80 mmHg) and angular velocities (ω = 30–52 kRPM). The obtained flow rate is compared between the cases to assess the effect of the impeller's design and working conditions on the pump performance. The comparative risk of shear-induced platelet activation is estimated using the statistical median of the stress-accumulation values calculated along streamlines. The risk of hemolysis is estimated using the average exposure time to shear stress above a threshold (τ > 425 Pa). The results reveal that the shape of the impeller's hub has a great impact on the flow patterns, performance, and risk of blood damage, as well as the angular velocity. The highest flow rate (Q = 3.7 L/min) and efficiency (η = 11.3 %) were achieved using a straight hub (α = 0○). Similarly, for the same condition of flow and pressure, the straight hub impeller has the lowest blood damage risk parameters. This study shed light on the effect of pump design on the performance and risk of blood damage, indicating the roles of the hub shape and angular velocity as dominant parameters.
KW - Computational fluid dynamics
KW - Hemolysis
KW - Impeller design
KW - Mechanical circulatory support device
KW - Platelets activation
UR - http://www.scopus.com/inward/record.url?scp=85197411102&partnerID=8YFLogxK
U2 - 10.1016/j.compbiomed.2024.108695
DO - 10.1016/j.compbiomed.2024.108695
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 38968763
AN - SCOPUS:85197411102
SN - 0010-4825
VL - 179
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
M1 - 108695
ER -