The impact of prostate biopsy on patient well-being: A prospective study of voiding impairment

Amnon Zisman*, Dan Leibovici, Judith Kleinmann, Amir Cooper, Yoram Siegel, Arie Lindner

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Purpose: We studied the possible association of transrectal ultrasound guided prostate biopsy with voiding impairment. Materials and Methods: A total of 211 consecutive patients were prospectively enrolled. International Prostate Symptom Score (I-PSS), subjective voiding complaints and retention were recorded in 3 personal interviews before biopsy, and on postoperative days 7 and 30. Results: Of the 204 patients who voided via the urethra at biopsy 52 (25%) reported subjective voiding impairment on postoperative day 7, including 12% who defined difficult voiding as mild - 1 to 2 points on a 0 to 5 scale, 8% as moderate - 3/5 and 5% as severe - 4 to 5/5. In 5 of the latter cases (2.5%) acute urinary retention necessitated urethral catheter insertion. Transition zone volume, which was 42 ml. or larger in all patients in urinary retention, was the only independent variable associated with patient report of subjective difficult voiding and acute urinary retention during week 1 after biopsy (p = 0.03). Baseline I-PSS greater than 20 points indicated a risk of an acute transient increase in I-PSS on postoperative day 7. Conclusions: Transient voiding impairment may be precipitated by ultrasound guided prostate biopsy. To decrease this morbidity appropriate evaluation and possible treatment for bladder outlet obstruction are justified in patients with a larger transition zone and in those with preoperative baseline I-PSS greater than 20 points.

Original languageEnglish
Pages (from-to)2242-2246
Number of pages5
JournalJournal of Urology
Issue number6
StatePublished - 2001


  • Biopsy
  • Prostate
  • Prostatic neoplasms
  • Quality of life
  • Questionnaires


Dive into the research topics of 'The impact of prostate biopsy on patient well-being: A prospective study of voiding impairment'. Together they form a unique fingerprint.

Cite this