TY - JOUR
T1 - The impact of early testicular sperm extraction or cryopreservation on the outcome of intracytoplasmic sperm injection - A randomized controlled study
AU - Dirnfeld, M.
AU - Paz, M.
AU - Yshai, D.
AU - Calderon, I.
AU - Lahav-Baratz, S.
AU - Koifman, M.
AU - Shiloh, H.
AU - Abramovici, H.
AU - Bider, D.
PY - 2003/6/1
Y1 - 2003/6/1
N2 - Purpose: To compare the outcome of sperm extraction 24 h before ovum pickup and on the day of oocyte retrieval. Methods: A controlled study was performed to compare the outcome of 90 sperm extractions and in vitro sperm injection cycles performed in 54 patients. Results: Available fresh sperm for the sperm injection procedure and cryopreservation obtained on the day of ovum pickup were similar to sperm collected 1 day before (33.3% vs. 39.4%, respectively). Fertilization rate obtained with fresh sperm was also similar (48.9% vs. 54%), respectively. Clinical pregnancy rate was 38% vs. 22% per embryo transfer, respectively (P = 0.235). When comparing an additional 24 cycles with cryopreservation of sperm retrieved on the day of ovum pickup, as well as a day previously, no significance was noted in the parameters. Conclusions: Sperm retrieved 24 h before oocyte retrieval and used as fresh or frozen-thawed for sperm injection are as effective as those used on the day of ovum pickup.
AB - Purpose: To compare the outcome of sperm extraction 24 h before ovum pickup and on the day of oocyte retrieval. Methods: A controlled study was performed to compare the outcome of 90 sperm extractions and in vitro sperm injection cycles performed in 54 patients. Results: Available fresh sperm for the sperm injection procedure and cryopreservation obtained on the day of ovum pickup were similar to sperm collected 1 day before (33.3% vs. 39.4%, respectively). Fertilization rate obtained with fresh sperm was also similar (48.9% vs. 54%), respectively. Clinical pregnancy rate was 38% vs. 22% per embryo transfer, respectively (P = 0.235). When comparing an additional 24 cycles with cryopreservation of sperm retrieved on the day of ovum pickup, as well as a day previously, no significance was noted in the parameters. Conclusions: Sperm retrieved 24 h before oocyte retrieval and used as fresh or frozen-thawed for sperm injection are as effective as those used on the day of ovum pickup.
KW - Cryopreservation
KW - ICSI
KW - Nonobstructive azoospermia
KW - TESE
UR - http://www.scopus.com/inward/record.url?scp=0038649180&partnerID=8YFLogxK
U2 - 10.1023/A:1024116326465
DO - 10.1023/A:1024116326465
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AN - SCOPUS:0038649180
SN - 1058-0468
VL - 20
SP - 205
EP - 209
JO - Journal of Assisted Reproduction and Genetics
JF - Journal of Assisted Reproduction and Genetics
IS - 6
ER -