The immune system in severe ovarian hyperstimulation syndrome

R. Orvieto, Z. Ben-Rafael*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Recently, evidence has accumulated concerning the interaction between the immune and reproductive systems that results from sharing certain lymphohematopoietic cytokines and their receptors. Furthermore, several cytokines have been implicated as having a role in the prediction and pathophysiology of ovarian hyperstimulation syndrome (OHSS). The hitherto known studies concerning the role of the immune system in OHSS, together with a hypothesis regarding the role of interleukin-2 as a possible culprit of this complication, are presented.

Original languageEnglish
Pages (from-to)1180-1182
Number of pages3
JournalIsrael Journal of Medical Sciences
Issue number12
StatePublished - Dec 1996
Externally publishedYes


  • Cytokines
  • Interleukin 2
  • Ovarian hyperstimulation syndrome
  • Pathophysiology


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