The Human Affectome

Daniela Schiller*, Alessandra N.C. Yu, Nelly Alia-Klein, Susanne Becker, Howard C. Cromwell, Florin Dolcos, Paul J. Eslinger, Paul Frewen, Andrew H. Kemp, Edward F. Pace-Schott, Jacob Raber, Rebecca L. Silton, Elka Stefanova, Justin H.G. Williams, Nobuhito Abe, Moji Aghajani, Franziska Albrecht, Rebecca Alexander, Silke Anders, Oriana R. AragónJuan A. Arias, Shahar Arzy, Tatjana Aue, Sandra Baez, Michela Balconi, Tommaso Ballarini, Scott Bannister, Marlissa C. Banta, Karen Caplovitz Barrett, Catherine Belzung, Moustafa Bensafi, Linda Booij, Jamila Bookwala, Julie Boulanger-Bertolus, Sydney Weber Boutros, Anne Kathrin Bräscher, Antonio Bruno, Geraldo Busatto, Lauren M. Bylsma, Catherine Caldwell-Harris, Raymond C.K. Chan, Nicolas Cherbuin, Julian Chiarella, Pietro Cipresso, Hugo Critchley, Denise E. Croote, Heath A. Demaree, Thomas F. Denson, Brendan Depue, Birgit Derntl, Joanne M. Dickson, Sanda Dolcos, Anat Drach-Zahavy, Olga Dubljević, Tuomas Eerola, Dan Mikael Ellingsen, Beth Fairfield, Camille Ferdenzi, Bruce H. Friedman, Cynthia H.Y. Fu, Justine M. Gatt, Beatrice de Gelder, Guido H.E. Gendolla, Gadi Gilam, Hadass Goldblatt, Anne Elizabeth Kotynski Gooding, Olivia Gosseries, Alfons O. Hamm, Jamie L. Hanson, Talma Hendler, Cornelia Herbert, Stefan G. Hofmann, Agustin Ibanez, Mateus Joffily, Tanja Jovanovic, Ian J. Kahrilas, Maria Kangas, Yuta Katsumi, Elizabeth Kensinger, Lauren A.J. Kirby, Rebecca Koncz, Ernst H.W. Koster, Kasia Kozlowska, Sören Krach, Mariska E. Kret, Martin Krippl, Kwabena Kusi-Mensah, Cecile D. Ladouceur, Steven Laureys, Alistair Lawrence, Chiang shan R. Li, Belinda J. Liddell, Navdeep K. Lidhar, Christopher A. Lowry, Kelsey Magee, Marie France Marin, Veronica Mariotti, Loren J. Martin, Hilary A. Marusak, Annalina V. Mayer, Amanda R. Merner, Jessica Minnier, Jorge Moll, Robert G. Morrison, Matthew Moore, Anne Marie Mouly, Sven C. Mueller, Andreas Mühlberger, Nora A. Murphy, Maria Rosaria Anna Muscatello, Erica D. Musser, Tamara L. Newton, Michael Noll-Hussong, Seth Davin Norrholm, Georg Northoff, Robin Nusslock, Hadas Okon-Singer, Thomas M. Olino, Catherine Ortner, Mayowa Owolabi, Caterina Padulo, Romina Palermo, Rocco Palumbo, Sara Palumbo, Christos Papadelis, Alan J. Pegna, Silvia Pellegrini, Kirsi Peltonen, Brenda W.J.H. Penninx, Pietro Pietrini, Graziano Pinna, Rosario Pintos Lobo, Kelly L. Polnaszek, Maryna Polyakova, Christine Rabinak, S. Helene Richter, Thalia Richter, Giuseppe Riva, Amelia Rizzo, Jennifer L. Robinson, Pedro Rosa, Perminder S. Sachdev, Wataru Sato, Matthias L. Schroeter, Susanne Schweizer, Youssef Shiban, Advaith Siddharthan, Ewa Siedlecka, Robert C. Smith, Hermona Soreq, Derek P. Spangler, Emily R. Stern, Charis Styliadis, Gavin B. Sullivan, James E. Swain, Sébastien Urben, Jan Van den Stock, Michael A. vander Kooij, Mark van Overveld, Tamsyn E. Van Rheenen, Michael B. VanElzakker, Carlos Ventura-Bort, Edelyn Verona, Tyler Volk, Yi Wang, Leah T. Weingast, Mathias Weymar, Claire Williams, Megan L. Willis, Paula Yamashita, Roland Zahn, Barbra Zupan, Leroy Lowe*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Over the last decades, theoretical perspectives in the interdisciplinary field of the affective sciences have proliferated rather than converged due to differing assumptions about what human affective phenomena are and how they work. These metaphysical and mechanistic assumptions, shaped by academic context and values, have dictated affective constructs and operationalizations. However, an assumption about the purpose of affective phenomena can guide us to a common set of metaphysical and mechanistic assumptions. In this capstone paper, we home in on a nested teleological principle for human affective phenomena in order to synthesize metaphysical and mechanistic assumptions. Under this framework, human affective phenomena can collectively be considered algorithms that either adjust based on the human comfort zone (affective concerns) or monitor those adaptive processes (affective features). This teleologically-grounded framework offers a principled agenda and launchpad for both organizing existing perspectives and generating new ones. Ultimately, we hope the Human Affectome brings us a step closer to not only an integrated understanding of human affective phenomena, but an integrated field for affective research.

Original languageEnglish
Article number105450
JournalNeuroscience and Biobehavioral Reviews
Volume158
DOIs
StatePublished - Mar 2024

Funding

FundersFunder number
National Institute of Environmental Health SciencesRO1 ES019672
National Institute of Environmental Health Sciences
U.S. Department of DefenseW81XWH-15-1-0521
U.S. Department of Defense
Parkinson's Disease Foundation
Research Foundation for the State University of New York
Alzheimer's AssociationSG-20-725707-ReDLat
Alzheimer's Association
U.S. Department of DefenseW81XWH-17-1-0193, R21 CA223461, RF1 AG059088, RF1 AG058273, U19 AT010829, R21 ES027943, R01 NS080866, R01 HL140182, R21 AG065914
U.S. Department of Defense
Northwood Trust
Biotechnology and Biological Sciences Research Council
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
U.S. Navy
California Department of Fish and GameDE2319/6-1, DE2319/9-1
California Department of Fish and Game
Office of Naval Research Multidisciplinary UniversityR01MH099007, N00014-15-1-2809, R01MH101096, R01MH103241
CHERISH-DE
CaNVAS1R01NS114045–01
Alzheimer's AssociationR01 MH126981, R33 MH107589, R01 MH111794
Alzheimer's Association
NASA NASA80NSSC19K0498 –P00001
National Aeronautics and Space AdministrationNNX15AK13G
National Aeronautics and Space Administration
Ministero della Salute
Bundesministerium für Bildung und Forschung
Colorado Office of Economic Development and International Trade
Fondo Nacional de Desarrollo Científico y Tecnológico1210195, 15150012, 1220995, 1210176, ANID/PIA/ANILLOS ACT210096
Fondo Nacional de Desarrollo Científico y Tecnológico
Memphis Research ConsortiumG0802594
Memphis Research Consortium
Consejo Nacional de Investigaciones Científicas y Técnicas
Hessisches Ministerium für Wissenschaft und KunstPP00P1_183709, PP00P1_150492
Hessisches Ministerium für Wissenschaft und Kunst
Michael J. Fox Foundation for Parkinson's ResearchMJFF-11362
Michael J. Fox Foundation for Parkinson's Research
Misophonia Research Fund
ARISESR01NS115944-01, 3U24HG009780-03S5
FONCYT-PICT2017-1818, 2017-1820
Sub-Saharan Africa Conference on StrokeD43TW012030, 1R13NS115395–01A1
Australian Research Council
Veterans Affairs Canada
Center for African StudiesMH100117, DAO51361, MH077908
Center for African Studies
National Institutes of HealthR01AG057234
National Institutes of Health
Alexander von Humboldt-Stiftung
University of MelbourneR01MH107495, 31871114, R01MH111682, R01MH100122, R01MH110364
University of Melbourne
SparksCRSK-3_190490
Sparks
Max-Planck-Gesellschaft
Fonds de Recherche du Québec - SantéMH104325, MH118218, MH101750
Fonds de Recherche du Québec - Santé
Human Brain Project SGA3945539
Brain and Behavior Research Foundation
National Center for Complementary and Integrative HealthR41AT011390, R01AT010005
National Center for Complementary and Integrative Health
eHealthSax Initiative of the Sächsische Aufbaubank
Program on Philanthropy and Social Innovation
Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja175090
Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja
Alexander von Humboldt Professur
Norwegian Research Council/Marie Sklodowska-Curie ActionsR01MH122611, FRICON/COFUND-240553/F20, R01MH123069
Beijing Municipal Science and Technology Commission, Adminitrative Commission of Zhongguancun Science ParkZ161100000216138
Beijing Municipal Science and Technology Commission, Adminitrative Commission of Zhongguancun Science Park
National Key Research and Development Program of China2016YFC0906402
National Key Research and Development Program of China
Wellcome Trust209127/Z/17
Wellcome Trust
International Max Planck Research School for Environmental, Cellular and Molecular Microbiology
Canadian Institutes of Health Research
National Health and Medical Research Council1088785
National Health and Medical Research Council
Centre of Excellence in Cognition and its Disorders, Australian Research CouncilCE110001021
Centre of Excellence in Cognition and its Disorders, Australian Research Council
National Institutes of Health
State University of New York
Colorado Office of Economic Development and International TradeCTGG1-2020-3064
Colorado Office of Economic Development and International Trade
Deutsche Forschungsgemeinschaft
National Science FoundationT32 AG055378, F31 AG067269, KR 3803/9–1, KR 3803/11–1, GVPRS0014D9
National Science Foundation
Global Brain Health Institute
Rainwater Foundation
Canadian Institutes of Health Research
National Institute on Aging
National Institute on Aging
Agence Nationale de la RechercheANR-11-IDEX-007
Agence Nationale de la Recherche
Japan Society for the Promotion of Science19H00628, 17H06054
Japan Society for the Promotion of Science
Alzheimer’s Therapeutic Research Institute
Scottish Government Strategic Research Programme
National Health and Medical Research Council
University of Illinois System
National Institute on Drug Abuse
Vital Projects Fund, Inc.ANR-15-FRAL-0002
Bundesministerium für Bildung und ForschungFKZ 01GI1007A
Bundesministerium für Bildung und Forschung
National Institute on Drug AbuseR01 DA047336, R01 DA047094
National Institute on Drug Abuse
Université de LyonANR-11-LABX-0042
Université de Lyon
Helen Corley Petit Scholarship in Liberal Arts and Sciences
National Natural Science Foundation of China81571317
National Natural Science Foundation of China
National Institute of Mental HealthK23MH117280, MH109638, R03MH110812-02
National Institute of Mental Health
Fonds de Recherche du Québec - SantéSCHR 774/5–1
Fonds de Recherche du Québec - Santé
LIFE programme
Ministero dell’Istruzione, dell’Università e della Ricerca201597WTTM
Ministero dell’Istruzione, dell’Università e della Ricerca
Health and Care Research WalesRfPPB-18-1502
Health and Care Research Wales
SIRENU54HG007479, R01NS107900
National Alliance for Research on Schizophrenia and Depression
Peter F. McManus Charitable Trust
Sächsische AufbaubankWE 4801/3–1, WE 4801/6–1
Sächsische Aufbaubank
Low-End Virtual Reality SystemsAPP1122816, PE-2013-0235594
National Institute of Mental HealthR21MH116263
National Institute of Mental Health
Canadian Department of National Defense
University of South Carolina
SIBS Gen GenR01NS107900-02S1

    Keywords

    • Affect
    • Allostasis
    • Arousal
    • Emotion
    • Enactivism
    • Feeling
    • Framework
    • Mood
    • Motivation
    • Self
    • Sensation
    • Stress
    • Valence
    • Wellbeing

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