@article{95c79ea1e3fc411b890233efea07e210,
title = "The herpes simplex virus amplicon IV. Efficient expression of a chimeric chicken ovalbumin gene amplified within defective virus genomes",
abstract = "cDNA sequences of the chicken ovalbumin gene were fused to an α (immediate early) promoter of herpes simplex virus and to genomic ovalbumin 3′-flanking sequences. The chimeric α-ovalbumin gene was introduced into defective virus genomes which were stably propagated in serially passaged virus stocks in the presence of helper virus. Analyses of polypeptides synthesized in cells infected with the resultant defective virus stocks revealed the abundant expression of the chimeric α-ovalbumin gene. The presence of introns was not essential for this expression.",
author = "Kwong, {Ann D.} and Niza Frenkel",
note = "Funding Information: These studies were supported by U. S. Public Health Service Research Grants AI-15488 and CA-19264 from the National Cancer Institute and by National Science Foundation Grant PCM 8118303. A.D.K. is a predoctoral trainee supported by Training Grant PHS AI 07182. We thank Dr. W. B. O{\textquoteright}Malley for the gift of the pOV12 and pOV230 clones, and Ms. Malera Traylor for her skillful technical help.",
year = "1985",
month = apr,
day = "30",
doi = "10.1016/0042-6822(85)90351-4",
language = "אנגלית",
volume = "142",
pages = "421--425",
journal = "Virology",
issn = "0042-6822",
publisher = "Academic Press Inc.",
number = "2",
}