The first general route for efficient synthesis of 18O labelled alcohols using the HOF·CH3CN complex

Julia Gatenyo, Inna Vints, Shlomo Rozen

Research output: Contribution to journalArticlepeer-review

Abstract

A mild and very efficient method for converting boronic acids to alcohols has been developed using the acetonitrile complex of hypofluorous acid HOF·CH3CN. Employing 18O-labeled water results in alcohols containing a heavy oxygen isotope. The reactions were performed at room temperature, within a few minutes and in excellent yields.

Original languageEnglish
Pages (from-to)7379-7381
Number of pages3
JournalChemical Communications
Volume49
Issue number67
DOIs
StatePublished - 25 Jul 2013

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