The first, general, highly efficient method for preparing tetrasubstituted epoxides using HOF·CH3CN

Shlomo Rozen; Elizabeth Golan

doi:10.1002/ejoc.200300082

The first, general, highly efficient method for preparing tetrasubstituted epoxides using HOF·CH₃CN

Shlomo Rozen^*
, Elizabeth Golan

^*Corresponding author for this work

School of Chemistry

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Tetrasubstituted epoxides, and especially electron-depleted ones, generally are difficult to prepare. HOF·CH₃CN complex, probably the best oxygen transfer agent known today, epoxidizes tetrasubstituted alkenes at 0 °C in a matter of minutes or less in excellent yields. HOF·CH₃CN complex is very easy to prepare by bubbling diluted fluorine (commercial) through aqueous acetonitrile.

Original language	English
Pages (from-to)	1915-1917
Number of pages	3
Journal	European Journal of Organic Chemistry
Issue number	10
DOIs	https://doi.org/10.1002/ejoc.200300082
State	Published - May 2003

Keywords

Epoxidations
Fluorine
HOF·CHCN
Olefins
Synthetic methods

Access to Document

10.1002/ejoc.200300082

Cite this

@article{873a2871d28d4919af29ed66efe41dbe,

title = "The first, general, highly efficient method for preparing tetrasubstituted epoxides using HOF·CH3CN",

abstract = "Tetrasubstituted epoxides, and especially electron-depleted ones, generally are difficult to prepare. HOF·CH3CN complex, probably the best oxygen transfer agent known today, epoxidizes tetrasubstituted alkenes at 0 °C in a matter of minutes or less in excellent yields. HOF·CH3CN complex is very easy to prepare by bubbling diluted fluorine (commercial) through aqueous acetonitrile.",

keywords = "Epoxidations, Fluorine, HOF·CHCN, Olefins, Synthetic methods",

author = "Shlomo Rozen and Elizabeth Golan",

year = "2003",

month = may,

doi = "10.1002/ejoc.200300082",

language = "אנגלית",

pages = "1915--1917",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley",

number = "10",

}

TY - JOUR

T1 - The first, general, highly efficient method for preparing tetrasubstituted epoxides using HOF·CH3CN

AU - Rozen, Shlomo

AU - Golan, Elizabeth

PY - 2003/5

Y1 - 2003/5

N2 - Tetrasubstituted epoxides, and especially electron-depleted ones, generally are difficult to prepare. HOF·CH3CN complex, probably the best oxygen transfer agent known today, epoxidizes tetrasubstituted alkenes at 0 °C in a matter of minutes or less in excellent yields. HOF·CH3CN complex is very easy to prepare by bubbling diluted fluorine (commercial) through aqueous acetonitrile.

AB - Tetrasubstituted epoxides, and especially electron-depleted ones, generally are difficult to prepare. HOF·CH3CN complex, probably the best oxygen transfer agent known today, epoxidizes tetrasubstituted alkenes at 0 °C in a matter of minutes or less in excellent yields. HOF·CH3CN complex is very easy to prepare by bubbling diluted fluorine (commercial) through aqueous acetonitrile.

KW - Epoxidations

KW - Fluorine

KW - HOF·CHCN

KW - Olefins

KW - Synthetic methods

UR - https://www.scopus.com/pages/publications/0037573551

U2 - 10.1002/ejoc.200300082

DO - 10.1002/ejoc.200300082

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0037573551

SN - 1434-193X

SP - 1915

EP - 1917

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 10

ER -

The first, general, highly efficient method for preparing tetrasubstituted epoxides using HOF·CH₃CN

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this