The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance

Keyphrases

• Regulatory Elements 100%
• Tissue Specificity 50%
• High Similarity 50%
• Human Genes 50%
• Human Genome 50%
• Target Gene Expression 50%
• Genomic Distance 50%
• Human Cell Lines 50%
• Distal Enhancer 50%
• Chromatin Interactions 50%
• Gene Expression Stability 50%
• Robust Stability 50%
• Comprehensive Map 50%
• Regulatory Programs 50%
• Evolutionary Stability 50%
• Hi-C Data 50%
• Redundant Enhancers 50%
• Primary Contact 50%
• Active Enhancer 50%
• Multiple Cell Lines 50%
• Promoter/enhancer 50%
• DNA Segments 50%
• High Enrichment 50%
• Gene Enhancer 50%

Biochemistry, Genetics and Molecular Biology

• Promoter Region 100%
• Enhancer Region 100%
• Gene Expression 12%
• Regulatory Element 12%
• Tissue Specificity 6%
• Transcription 6%
• Human Genome 6%
• Chromatin 6%
• Genomics 6%