The Financial Impact of Fractionation Scheme and Treatment Planning Method for Rectal Cancer in the United States

Assaf Moore, Robert B. Den, Noa Gordon, Michal Sarfaty, Yulia Kundel, Baruch Brenner, Daniel A. Goldstein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

We performed a population-based analysis of the total annual cost of various radiotherapy regimens for rectal cancer in the United States. The target population was estimated using the Surveillance, Epidemiology, and End Results database and radiotherapy costs by the Hospital Outpatient Prospective Payment System. Short-course radiotherapy may have the potential to save US $106 to 232 million annually compared with long-course chemoradiotherapy, likely without impacting outcomes. Intensity-modulated radiotherapy increases the cost of treatment by 34% and 50% for short-course and long-course chemoradiotherapy, respectively.

Original languageEnglish
Pages (from-to)209-217
Number of pages9
JournalClinical Colorectal Cancer
Volume18
Issue number3
DOIs
StatePublished - Sep 2019

Keywords

  • Chemoradiation
  • Hypofractionation
  • Intensity-modulated radiotherapy
  • Radiotherapy
  • Short-course radiotherapy

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