TY - JOUR
T1 - The evolution of toxic anterior segment syndrome
AU - Shouchane-Blum, Karny
AU - Dotan, Assaf
AU - Bahar, Irit
N1 - Publisher Copyright:
© 2018 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Purpose of reviewToxic anterior segment syndrome (TASS) is a surgical complication resulting from a noninfectious inflammatory reaction to substances used during intraocular ophthalmic surgery. Continuous reporting of new information concerning risk factors and possible causes is critical for preventing this condition.Recent findingsThe diagnosis of TASS is clinical and its main features are well known. However, new causes of TASS are emerging and being reported, as are new treatment options for managing the inflammation or its complications, and prevention guidelines are being updated. This article presents current and novel information regarding these topics.SummaryEducating the medical community regarding potential causes of TASS and its prevention is necessary for improving management of TASS. Thorough investigations and reports of TASS cases are a fundamental step in achieving this goal. Still, as the complete eradication of TASS solely through prevention is unlikely, further studies regarding TASS's pathophysiology, systemic and ocular risk factors, and new treatment options are necessary.
AB - Purpose of reviewToxic anterior segment syndrome (TASS) is a surgical complication resulting from a noninfectious inflammatory reaction to substances used during intraocular ophthalmic surgery. Continuous reporting of new information concerning risk factors and possible causes is critical for preventing this condition.Recent findingsThe diagnosis of TASS is clinical and its main features are well known. However, new causes of TASS are emerging and being reported, as are new treatment options for managing the inflammation or its complications, and prevention guidelines are being updated. This article presents current and novel information regarding these topics.SummaryEducating the medical community regarding potential causes of TASS and its prevention is necessary for improving management of TASS. Thorough investigations and reports of TASS cases are a fundamental step in achieving this goal. Still, as the complete eradication of TASS solely through prevention is unlikely, further studies regarding TASS's pathophysiology, systemic and ocular risk factors, and new treatment options are necessary.
KW - guidelines
KW - risk factors
KW - toxic anterior segment syndrome
KW - treatment
UR - http://www.scopus.com/inward/record.url?scp=85057561838&partnerID=8YFLogxK
U2 - 10.1097/ICU.0000000000000540
DO - 10.1097/ICU.0000000000000540
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C2 - 30489360
AN - SCOPUS:85057561838
SN - 1040-8738
VL - 30
SP - 50
EP - 55
JO - Current Opinion in Ophthalmology
JF - Current Opinion in Ophthalmology
IS - 1
ER -