The Escherichia coli CRISPR system protects from λ lysogenization, lysogens, and prophage induction

Rotem Edgar, Udi Qimron*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

139 Scopus citations

Abstract

We show that phage lysogenization, lysogens, and prophage induction are all targeted by CRISPR. The results demonstrate that genomic DNA is not immune to the CRISPR system, that the CRISPR system does not require noncytoplasmic elements, and that the system protects from phages entering and exiting the lysogenic cycle.

Original languageEnglish
Pages (from-to)6291-6294
Number of pages4
JournalJournal of Bacteriology
Volume192
Issue number23
DOIs
StatePublished - Dec 2010

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