The erythrocyte adhesiveness/aggregation test for the detection of an acute phase response and for the assessment of its intensity

N. Maharshak, I. Shapira, R. Rotstein, J. Serov, S. Aharonov, T. Mardi, A. Twig, A. Rubinstein, M. Kofler, Shlomo Berliner, D. Zeltser

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We have developed a simple slide test and image analysis to reveal the state of erythrocyte adhesiveness/aggregation in the peripheral blood of patients with various degrees of the humoral acute phase response. The significant correlation between the results of the erythrocyte adhesiveness/aggregation test (EAAT), the erythrocyte sedimentation rate and fibrinogen concentration support the notion that it is possible to use the EAAT as a marker for the intensity of the acute phase response. Within a group of 860 individuals, we were able to differentiate effectively between groups of patients with a different intensity of humoral acute phase response. The present study confirms previous observations that support the applicability of the EAAT to routine clinical practice.

Original languageEnglish
Pages (from-to)205-210
Number of pages6
JournalClinical and Laboratory Haematology
Volume24
Issue number4
DOIs
StatePublished - 2002
Externally publishedYes

Keywords

  • Erythrocyte adhesiveness/aggregation inflammation

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